Synthesis of 2-aminothiazoles from styrene derivatives mediated by 1,3-dibromo-5,5-dimethylhydrantoin (DBH)
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DOI: 10.1016/j.tet.2018.05.021
Abstract: Abstract An efficient procedure for the synthesis of 2-aminothiazoles via DBH-mediated oxidative cyclization of styrenes and thioureas is reported. Various alkenes were successfully transformed to the corresponding 2-aminothiazoles in yields of 10–81% via a two-step… read more here.
Keywords: synthesis aminothiazoles; styrene derivatives; aminothiazoles styrene; derivatives mediated ... See more keywords