Acetylornithine aminotransferase TM1785 performs multiple functions in the hyperthermophile Thermotoga maritima.
Sign Up to like & getrecommendations! Published in 2021 at "FEBS letters"
DOI: 10.1002/1873-3468.14222
Abstract: The hyperthermophilic bacterium Thermotoga maritima peptidoglycan contains unusual D-lysine alongside typical D-alanine and D-glutamate. We previously identified lysine racemase and threonine dehydratase, but knowledge of D-amino acid metabolism remains limited. Herein, we identified and characterized… read more here.
Keywords: aminotransferase; thermotoga maritima; aminotransferase tm1785; acetylornithine aminotransferase ... See more keywords
New pediatric percentiles of liver enzyme serum levels (alanine aminotransferase, aspartate aminotransferase, γ‐glutamyltransferase): Effects of age, sex, body mass index, and pubertal stage
Sign Up to like & getrecommendations! Published in 2018 at "Hepatology"
DOI: 10.1002/hep.29542
Abstract: The present study aims to clarify the effects of sex, age, body mass index (BMI), and puberty on transaminase serum levels in children and adolescents and to provide new age‐ and sex‐related percentiles for alanine… read more here.
Keywords: aminotransferase; age; serum levels; age sex ... See more keywords
Function indices of liver and kidney and haematological parameters of male Wistar rats after oral administration of aqueous extract of Terminalia avicennioides root barks
Sign Up to like & getrecommendations! Published in 2018 at "Comparative Clinical Pathology"
DOI: 10.1007/s00580-018-2836-9
Abstract: Terminalia avicennioides is a member of the Combretaceae family with a lot of medicinal properties. This study aims to investigate the effects of aqueous extract of T. avicennioides root barks on biochemical and haematological parameters… read more here.
Keywords: liver kidney; aminotransferase; terminalia avicennioides; haematological parameters ... See more keywords
Combination of quantitative hepatitis B core antibody (qHBcAb) and aspartate aminotransferase (AST) can accurately diagnose immune tolerance of chronic hepatitis B virus infection based on liver biopsy.
Sign Up to like & getrecommendations! Published in 2020 at "Clinics and research in hepatology and gastroenterology"
DOI: 10.1016/j.clinre.2020.10.008
Abstract: BACKGROUND AND AIMS Immune tolerance is defined as HBeAg positive, high hepatitis B virus load (HBV), persistent normal alanine aminotransferase (ALT), no or slight inflammation or fibrosis in liver histology. However, it is still unclear… read more here.
Keywords: aminotransferase; hepatitis; immune tolerance; ast ... See more keywords
Crystal structure of a novel type of ornithine δ-aminotransferase from the hyperthermophilic archaeon Pyrococcus horikoshii.
Sign Up to like & getrecommendations! Published in 2022 at "International journal of biological macromolecules"
DOI: 10.1016/j.ijbiomac.2022.03.114
Abstract: Ornithine δ-aminotransferase (Orn-AT) activity was detected for the enzyme annotated as a γ-aminobutyrate aminotransferase encoded by PH1423 gene from Pyrococcus horikoshii OT-3. Crystal structures of this novel archaeal ω-aminotransferase were determined for the enzyme in… read more here.
Keywords: plp; aminotransferase; pyrococcus horikoshii; ornithine aminotransferase ... See more keywords
Range of Normal Serum Aminotransferase Levels in Liver Transplant Recipients.
Sign Up to like & getrecommendations! Published in 2019 at "Transplantation proceedings"
DOI: 10.1016/j.transproceed.2019.04.062
Abstract: Alanine aminotransferase (ALT) and aspartate aminotransferase (AST) are used to monitor liver transplant recipients (LTR) but the reference range and context of its use is not well defined. We aimed to determine the healthy ranges… read more here.
Keywords: liver transplant; transplant recipients; aminotransferase; range ... See more keywords
Structure-function studies of the antibiotic target L,L-diaminopimelate aminotransferase from Verrucomicrobium spinosum reveal an unusual oligomeric structure.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemistry"
DOI: 10.1021/acs.biochem.0c00185
Abstract: While humans lack the biosynthetic pathways for meso-diaminopimelate and L-lysine, they are essential for bacterial survival and are therefore attractive targets for antibiotics. It was recently discovered that members of the Chlamydia family utilize a… read more here.
Keywords: aminotransferase; aminotransferase verrucomicrobium; structure; verrucomicrobium spinosum ... See more keywords
The consistency of aminotransferase analysis in China: a comparison of six mainstream aminotransferase routine methods and recalibration using human pooled serum preparations supplemented with human recombinant aminotransferases
Sign Up to like & getrecommendations! Published in 2022 at "Scandinavian Journal of Clinical and Laboratory Investigation"
DOI: 10.1080/00365513.2022.2025895
Abstract: Abstract Background: To evaluate the consistency of six mainstream homogeneous systems for aminotransferase measurements and improve the consistency of measurements by applying uniform calibrators. Methods: 200 individual samples were grouped into four sets for assays… read more here.
Keywords: using human; aminotransferase; group; recalibration ... See more keywords
Toxicity and biochemical responses induced by phosmet in rainbow trout (Oncorhynchus mykiss)
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DOI: 10.1093/toxres/tfab084
Abstract: Phosmet is a non-systemic organophosphorus insecticide exerting its toxicity by inhibiting acetylcholinesterase upon entering the body via contact, ingestion and inhalation. Data regarding its sublethal effects on fish are limited, and therefore, with this study… read more here.
Keywords: toxicity biochemical; biochemical responses; aminotransferase; responses induced ... See more keywords
Structural and functional studies of Spr1654: an essential aminotransferase in teichoic acid biosynthesis in Streptococcus pneumoniae
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DOI: 10.1098/rsob.170248
Abstract: Spr1654 from Streptococcus pneumoniae plays a key role in the production of unusual sugars, presumably functioning as a pyridoxal-5′-phosphate (PLP)-dependent aminotransferase. Spr1654 was predicted to catalyse the transferring of amino group to form the amino… read more here.
Keywords: biosynthesis; amino; aminotransferase; streptococcus pneumoniae ... See more keywords
D-alanine metabolism via D-Ala aminotransferase by marine Gammaproteobacteria, Pseudoalteromonas sp. CF6-2.
Sign Up to like & getrecommendations! Published in 2021 at "Applied and environmental microbiology"
DOI: 10.1128/aem.02219-21
Abstract: As the most abundant D-amino acid (DAA) in the ocean, D-alanine (D-Ala) is a key component of peptidoglycan in bacterial cell wall. However, the underlying mechanisms of bacterial metabolization of D-Ala through microbial food web… read more here.
Keywords: marine bacteria; ala aminotransferase; pseudoalteromonas cf6; aminotransferase ... See more keywords