Ranolazine depresses conduction of rapid atrial depolarizations in a beating rabbit heart model
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Interventional Cardiac Electrophysiology"
DOI: 10.1007/s10840-020-00865-0
Abstract: Previous clinical studies have shown that ranolazine (RAN) added to amiodarone (AMIO) might accelerate the termination of recent-onset atrial fibrillation. This study was undertaken to delineate possible mechanisms that contribute to the enhancement of the… read more here.
Keywords: conduction; amio; atrial depolarizations; ranolazine depresses ... See more keywords
Nicorandil mitigates amiodarone‐induced pulmonary toxicity and fibrosis in association with the inhibition of lung TGF‐β1/PI3K/Akt1‐p/mTOR axis in rats
Sign Up to like & getrecommendations! Published in 2022 at "Clinical and Experimental Pharmacology and Physiology"
DOI: 10.1111/1440-1681.13728
Abstract: The long‐term side effect of the antiarrhythmic drug, amiodarone (AMIO), such as lung toxicity, remains a critical clinical issue. The previous knowledge denotes diverse antioxidant, anti‐inflammatory, and antifibrotic properties of the anti‐anginal drug, nicorandil (NI).… read more here.
Keywords: pi3k akt1; mtor axis; amio; toxicity ... See more keywords