Solubility, thermodynamic properties, Hansen solubility parameter, and molecular simulation of amitriptyline hydrochloride (Form I) in fourteen organic pure solvents at different temperatures
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Molecular Liquids"
DOI: 10.1016/j.molliq.2021.116896
Abstract: Abstract The solubility of amitriptyline hydrochloride (AMT) (Form I) in fourteen mono-solvents, including {methanol, 2-methoxyethanol, ethanol, 2-ethoxyethanol, n-propanol, 2-propoxyethanol, n-butanol, 2-butoxyethanol, n-octanol, n-hexanol, n-heptanol, n-pentanol, N-Methyl pyrrolidone (NMP), N,N-Dimethylformamide (DMF)} was determined under 0.1 MPa… read more here.
Keywords: form; hansen solubility; form fourteen; amitriptyline hydrochloride ... See more keywords
Thermodynamic parameters of amitriptyline hydrochloride–additives at cloud point: effects of the ethanol–water mixed media
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DOI: 10.1080/00986445.2019.1657421
Abstract: Abstract Addition of organic solvents is known to change the properties of amphiphiles through modification of bulk phase. Amitriptyline hydrochloride (AMT) is a tricyclic amphiphilic drug which is usually used as an antidepressant. In drug… read more here.
Keywords: amitriptyline hydrochloride; effects ethanol; ethanol water; cloud point ... See more keywords
Effects of concurrent treatment with amitriptyline hydrochloride tablets and fluoxetine hydrochloride on therapeutic indicator levels in patients with depression
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DOI: 10.4314/tjpr.v18i2.26
Abstract: Purpose: To investigate the effects of combined treatment of amitriptyline hydrochloride tablets and fluoxetine hydrochloride on therapeutic indicator levels in depressive patients. Methods: Patients with depression ( n = 104) were divided into control group… read more here.
Keywords: fluoxetine hydrochloride; treatment; amitriptyline hydrochloride; hydrochloride tablets ... See more keywords