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   Articles with "aml cases" as a keyword



Flow cytometric immunophenotypic features of acute myeloid leukemia with mast cell differentiation.

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recommendations! Published in 2024 at "American journal of clinical pathology"

DOI: 10.1093/ajcp/aqae116

Abstract: OBJECTIVES Acute myeloid leukemia (AML) with mast cell (MC) differentiation was recently described as an aggressive subgroup of AML cases. The objectives of this study were to assess the flow cytometric immunophenotypic features of AML-MC… read more here.

Keywords: acute myeloid; mast cell; immunophenotypic features; aml cases ... See more keywords

Altered Immunophenotypes on Leukemic and/or Monocytic Cells from Acute Myeloid Leukemia Highly Predict for Nucleophosmin Gene Mutation

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recommendations! Published in 2019 at "Blood"

DOI: 10.1182/blood-2019-131733

Abstract: Introduction. Nucleophosmin gene mutation (NPM1mut) occurs in around 30% of acute myeloid leukemia (AML) patients, frequently linked with favourable prognosis in the absence of FLT3-ITDmut, which occurs in around 40% of NPM1mutAML. Therefore, more expeditious… read more here.

Keywords: blast; prior cd14; flt3; aml cases ... See more keywords

DNMT3A and NPM1 co-mutations in Acute Myeloid Leukemia (AML): A genomic landscape study

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recommendations! Published in 2025 at "Blood"

DOI: 10.1182/blood-2025-1722

Abstract: Background: Independent genomic alterations (GA) in the DNMT3A and NPM1 genes occur frequently in AML. While NPM1 mutation carries favorable prognosis in AML and has emerged as a target for anti-menin based treatments, co-mutation with… read more here.

Keywords: mut; dnmt3a npm1; aml; aml cases ... See more keywords

Characteristics and Prognosis of “Acute Promyelocytic Leukemia-like” Nucleophosmin-1-Mutated Acute Myeloid Leukemia in a Retrospective Patient Cohort

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recommendations! Published in 2024 at "Biomedicines"

DOI: 10.3390/biomedicines12102282

Abstract: Background: AML with NPM1 mutation is the largest subcategory of AML, representing about 35% of AML cases. It is characterized by CD34 negativity, which suggests a relatively differentiated state of the bulk of leukemic blasts.… read more here.

Keywords: apl like; mutated aml; npm1 mutated; acute promyelocytic ... See more keywords