Response to Dr. Bain's comment on our review article: Pure Erythroid Leukemia.
Sign Up to like & getrecommendations! Published in 2017 at "American journal of hematology"
DOI: 10.1002/ajh.24862
Abstract: Word Count: N/A Main Text Word Count: 339 Number of References: 3 # Correspondence: Josehp D. Khoury, MD Department of Hematopathology The University of Texas MD Anderson Cancer Center Houston, Texas 77030 Phone: 713-745-2387 Fax:… read more here.
Keywords: aml mrc; article; pel; mds ... See more keywords
Prognostic significance of MYC oncoprotein expression on survival outcome in patients with acute myeloid leukemia with myelodysplasia related changes (AML-MRC).
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DOI: 10.1016/j.leukres.2019.106194
Abstract: MYC is an oncoprotein that coordinates the expression of genes involved in metabolism, cell differentiation and survival in various types of malignancies. However, the underlying oncogenic mechanisms and the clinical significance of MYC expression in… read more here.
Keywords: aml mrc; expression; myc oncoprotein; myc ... See more keywords
Diagnosis and Treatment of Patients With Acute Myeloid Leukemia With Myelodysplasia-Related Changes (AML-MRC)
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DOI: 10.1093/ajcp/aqaa107
Abstract: Abstract Objectives Acute myeloid leukemia (AML) with myelodysplasia-related changes (AML-MRC) represents a high-risk and somewhat diverse subtype of AML, and substantial confusion exists about the pathologic evaluation needed for diagnosis, which can include the patient’s… read more here.
Keywords: aml mrc; diagnosis; treatment; pathology ... See more keywords
Molecular Classification of AML-MRC Reveals a Distinct Profile and Identifies MRC-like Patients with Poor Overall Survival
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DOI: 10.1182/blood-2019-128234
Abstract: Background: AML with myelodysplasia related changes (AML-MRC) is as specific WHO category with poor prognosis. It requires ≥ 20% of blasts, and (1) the history of MDS or MDS/MPN, or (2) "MDS related cytogenetic abnormalities",… read more here.
Keywords: mll munich; aml mrc; mrc; leukemia laboratory ... See more keywords
The need for rapid cytogenetics in the era of unique therapies for acute myeloid leukemia
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DOI: 10.1182/bloodadvances.2022008000
Abstract: Acute myeloid leukemia with myelodysplasia-related changes (AML-MRC) is a high-risk AML subtype with a reported frequency of 24% to 35% of all AMLs. 1-3 AMLs that develop after prior therapy (therapy-related myeloid neoplasms), with recurrent… read more here.
Keywords: acute myeloid; myeloid leukemia; aml mrc; therapy related ... See more keywords
[Venetoclax: A New Hope for Elderly Patients with Acute Myeloid Leukemia].
Sign Up to like & getrecommendations! Published in 2022 at "Acta medica portuguesa"
DOI: 10.20344/amp.17770
Abstract: Acute myeloid leukemia (AML) is a hematopoietic malignancy characterized by clonal proliferation, with increased incidence with advancing age. AML with myelodysplasia-related changes (AML-MRC) represents an AML subtype with a poor prognosis and challenging treatment, particularly… read more here.
Keywords: myeloid leukemia; elderly patients; venetoclax new; acute myeloid ... See more keywords