Cyclic GMP-AMP Triggers Asthma in an IL-33-Dependent Manner That Is Blocked by Amlexanox, a TBK1 Inhibitor
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DOI: 10.3389/fimmu.2019.02212
Abstract: Extracellular host-derived DNA, as one of damage associated molecular patterns (DAMPs), is associated with allergic type 2 immune responses. Immune recognition of such DNA generates the second messenger cyclic GMP-AMP (cGAMP) and induces type-2 immune… read more here.
Keywords: gmp amp; cgamp; amlexanox tbk1; cyclic gmp ... See more keywords