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Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1086
Abstract: Combined antihypertensive drugs have become the basic method of treating hypertension. Olmesartan and amlodipine, as representative drugs of angiotensin receptor blockers and calcium channel blockers, were developed as a compound formulation for antihypertensive treatment. The…
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Keywords:
time;
fasting fed;
fed conditions;
bioequivalence ... See more keywords
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Published in 2020 at "Optik"
DOI: 10.1016/j.ijleo.2020.165110
Abstract: Abstract In this study, two drugs named Amlodipine (AML) and Valsartan (VAL) related to the high blood pressure were simultaneously determined in synthetic mixtures and Valzomix tablet. For this purpose, the chemometric-assisted spectrophotometric method was…
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Keywords:
assisted spectrophotometric;
method;
spectrophotometric method;
chemometric assisted ... See more keywords
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Published in 2017 at "Journal of Pharmaceutical Analysis"
DOI: 10.1016/j.jpha.2017.06.001
Abstract: A sensitive and selective method has been proposed for the simultaneous determination of amlodipine (AML), valsartan (VAL) and hydrochlorothiazide (HCTZ) in human plasma by liquid chromatography–tandem mass spectrometry (LC–MS/MS). The analytes and their deuterated analogs…
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Keywords:
valsartan;
val;
method;
hctz ... See more keywords
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1
Published in 2022 at "Current Medical Research and Opinion"
DOI: 10.1080/03007995.2022.2030112
Abstract: Abstract Objective To compare changes in systolic and diastolic blood pressures (SBP, DBP) from baseline to following 8 weeks of treatment with a low dose combination of amlodipine 5 mg plus bisoprolol 5 mg versus up titration to…
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Keywords:
combination;
comparison;
dose combination;
amlodipine ... See more keywords
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Published in 2022 at "Clinical Toxicology"
DOI: 10.1080/15563650.2022.2131565
Abstract: Abstract Background: High dose insulin (HDI), an inotrope and vasodilator, is a standard therapy for calcium channel blocker (CCB) poisoning. HDI causes vasodilation by stimulating endothelial nitric oxide synthase (eNOS). Most literature supporting HDI for…
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Keywords:
non;
vasodilation;
amlodipine;
dose insulin ... See more keywords
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Published in 2023 at "Clinical toxicology"
DOI: 10.1080/15563650.2023.2200895
Abstract: ide (methylene blue), and extracorporeal membrane oxygenation. The total number of amlodipine cases managed by the Illinois Poison Center each year was compared to the number of amlodipine-related deaths, and proportional trends were compared to…
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Keywords:
calcium;
calcium channel;
amlodipine;
chloride ... See more keywords
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1
Published in 2022 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsac018
Abstract: BACKGROUND Two fixed-dose combination tablets of amlodipine with bisoprolol and amlodipine with candesartan were recently approved for the treatment of hypertension. OBJECTIVE Three UV spectrophotometric analytical methods were developed for the estimation of the above…
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Keywords:
candesartan;
method;
bisoprolol;
amlodipine ... See more keywords
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Published in 2017 at "Journal of Hypertension"
DOI: 10.1097/01.hjh.0000523463.74674.b2
Abstract: Objective: The purpose of this study was to assess in real practice the effect on adherence of a switch from a single- or two-pills therapy (SPT/FC) of perindopril and/or amlodipine to fixed-dose combination (FDC) of…
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Keywords:
adherence;
amlodipine;
dose combination;
perindopril amlodipine ... See more keywords
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Published in 2022 at "Journal of Cardiovascular Pharmacology"
DOI: 10.1097/fjc.0000000000001217
Abstract: Supplemental Digital Content is Available in the Text. Abstract: Nitrosamine contamination of generic valsartan was found in 2018. This study aimed to investigate whether long-term use of valsartan increases cancer risk. Patients prescribed valsartan or…
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Keywords:
valsartan;
incidence;
risk;
cancer risk ... See more keywords
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Published in 2021 at "International Journal of Clinical Practice"
DOI: 10.1111/ijcp.14957
Abstract: 1. The aim of their study was to compare, using a randomised clinical trial in hospitalised patients with COVID19 and primary hypertension, the effects of losartan and amlodipine using two primary outcomes: 30day mortality and…
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Keywords:
study;
randomised clinical;
amlodipine;
mortality ... See more keywords
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Published in 2022 at "BMJ Case Reports"
DOI: 10.1136/bcr-2022-249879
Abstract: The use of calcium channel blockers (CCBs) is associated with gingival enlargement, which adversely affects oral function, hygiene and aesthetics. Although CCB-induced gingival enlargement is a known adverse effect, it is rarely or never caused…
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Keywords:
gingival enlargement;
amlodipine;
ccb;
periodontal therapy ... See more keywords