Pharmacokinetics, Bioequivalence, and Safety Studies of Amlodipine Besylate in Healthy Subjects
Sign Up to like & getrecommendations! Published in 2022 at "Clinical Pharmacology in Drug Development"
DOI: 10.1002/cpdd.1064
Abstract: This study aimed to evaluate the bioequivalence of 2 amlodipine besylate tablet formulations, a generic formulation and an original formulation, and to investigate their pharmacokinetic and safety profiles. This study was designed as a randomized,… read more here.
Keywords: safety; besylate; concentration; bioequivalence ... See more keywords
Spectroscopic study and antioxidant activity of the inclusion complexes of cyclodextrins and amlodipine besylate drug
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Inclusion Phenomena and Macrocyclic Chemistry"
DOI: 10.1007/s10847-017-0768-7
Abstract: The aim of the study was to synthesize and characterization the inclusion complexes of amlodipine besylate (AML) drug with β-cyclodextrin (β-CD) and γ-cyclodextrin (γ-CD) which has antioxidating activity property. The guest/host interaction of AML with… read more here.
Keywords: antioxidant activity; inclusion; amlodipine besylate; drug ... See more keywords
Tuning the photocatalytic activity of TiO2 by Ag loading: Experimental and modelling studies for the degradation of amlodipine besylate drug
Sign Up to like & getrecommendations! Published in 2021 at "Ceramics International"
DOI: 10.1016/j.ceramint.2021.04.162
Abstract: Abstract In this research work, a heterogeneous photocatalytic process has been adopted for emergent pharmaceutical effluents treatment using amlodipine besylate as a contaminant molecule and Ag-TiO2 as a nanocatalyst. The influence of amlodipine besylate initial… read more here.
Keywords: tuning photocatalytic; amlodipine besylate; photocatalytic activity; tio2 ... See more keywords
Electrospun fixed dose formulations of amlodipine besylate and valsartan
Sign Up to like & getrecommendations! Published in 2018 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.08.008
Abstract: Graphical abstract Figure. No Caption available. Abstract Increasing numbers of elderly people require multi‐drug therapies. One route to improve adherence rates is to prepare fixed dose combinations (FDCs), in which multiple active ingredients are loaded… read more here.
Keywords: amlodipine besylate; drug; fixed dose; besylate valsartan ... See more keywords
Feasibility of developing hospital preparation by semisolid extrusion 3D printing: personalized amlodipine besylate chewable tablets
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceutical Development and Technology"
DOI: 10.1080/10837450.2022.2027965
Abstract: Abstract Semisolid extrusion (SSE) 3D printing is an emerging technology in personalized medicine. To address clinical multi-dose requirements, SSE has been explored to manufacture new preparations. In this study, amlodipine besylate (AMB) was the model… read more here.
Keywords: semisolid extrusion; chewable tablets; personalized amlodipine; medicine ... See more keywords
Application of MEKC and UPLC with Fluorescence Detection for Simultaneous Determination of Amlodipine Besylate and Bisoprolol Fumarate.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsaa136
Abstract: OBJECTIVE Two chromatographic methods were described for simultaneous determination of the antihypertensive drugs amlodipine besylate (AML) and bisoprolol fumarate (BIS). METHODS Method I applies micellar electrokinetic capillary chromatography using a deactivated fused silica capillary (25 cm… read more here.
Keywords: fluorescence detection; simultaneous determination; detection; amlodipine besylate ... See more keywords
Different Approaches in Manipulating Ratio Spectra for Analyzing Amlodipine besylate and Irbesartan Combination.
Sign Up to like & getrecommendations! Published in 2022 at "Journal of AOAC International"
DOI: 10.1093/jaoacint/qsac073
Abstract: BACKGROUND Hypertension is a key risk factor for ischemic heart disease and atherosclerosis. Most patients require a combination of antihypertensive medications to accomplish their therapeutic goals. Antihypertensive medicines such as calcium channel blockers and angiotensin… read more here.
Keywords: ratio spectra; besylate irbesartan; besylate; combination ... See more keywords
Simultaneous Determination of 15 Sulfonate Ester Impurities in Phentolamine Mesylate, Amlodipine Besylate, and Tosufloxacin Tosylate by LC-APCI-MS/MS
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Analytical Methods in Chemistry"
DOI: 10.1155/2019/4059765
Abstract: Sulfonate esters have been recognized as potential genotoxic impurities (PGIs) in pharmaceuticals. An LC-MS/MS method was developed and validated for the simultaneous determination of 15 sulfonate esters, including methyl, ethyl, propyl, isopropyl, and n-butyl esters… read more here.
Keywords: determination sulfonate; simultaneous determination; amlodipine besylate; phentolamine mesylate ... See more keywords
Method development and validation of HPLC tandem/mass spectrometry for quantification of perindopril arginine and amlodipine besylate combination in bulk and pharmaceutical formulations
Sign Up to like & getrecommendations! Published in 2017 at "Research in Pharmaceutical Sciences"
DOI: 10.4103/1735-5362.212048
Abstract: A well-characterized and fully validated ultra-high performance liquid chromatography-electrospray ionization-tandem mass spectrometric (UHPLC-ESI-MS/MS) method was developed to reliably analyze combination of perindopril arginine and amlodipine besylate in bulk and tablet formulations. The chromatographic separation was… read more here.
Keywords: perindopril arginine; tandem mass; amlodipine besylate; arginine amlodipine ... See more keywords
Development and Validation of UV-Derivative Spectroscopic and RP-HPLC Methods for the Determination of Amlodipine Besylate and Valsartan in Tablet Dosage form and Comparison of the Developed Methods by Student’s T-Test
Sign Up to like & getrecommendations! Published in 2017 at "Indian Journal of Pharmaceutical Education and Research"
DOI: 10.5530/ijper.51.4s.112
Abstract: Introduction: Hypertension is directly responsible for 51% of all stroke deaths and 45% of all coronary heart diseases worldwide. Amlodipine besylate is a calcium channel blocker used as an anti-hypertensive agent. Valsartan is an angiotensin… read more here.
Keywords: amlodipine besylate; developed methods; dosage; amlodipine ... See more keywords
Simultaneous Spectrophotometric Estimation of amlodipine besylate and Perindopril Erbumine in tablet Formulation
Sign Up to like & getrecommendations! Published in 2019 at "Research Journal of Pharmacy and Technology"
DOI: 10.5958/0974-360x.2019.01060.6
Abstract: Two simple, precise, accurate, specific and reproducible spectrophotometric methods have been developed for the simultaneous estimation of Amlodipine Besylate and Perindopril Erbumine in combined tablet dosage form using simultaneous equation and first order derivative methods.… read more here.
Keywords: estimation; amlodipine besylate; perindopril erbumine;