Glutamate Dehydrogenase Is Important for Ammonia Fixation and Amino Acid Homeostasis in Brain During Hyperammonemia
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DOI: 10.3389/fnins.2021.646291
Abstract: Impaired liver function may lead to hyperammonemia and risk for hepatic encephalopathy. In brain, detoxification of ammonia is mediated mainly by glutamine synthetase (GS) in astrocytes. This requires a continuous de novo synthesis of glutamate,… read more here.
Keywords: gdh; hyperammonemia; glutamate; ammonia ... See more keywords