Novel aspects of glutamine synthetase in ammonia homeostasis
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DOI: 10.1016/j.neuint.2020.104809
Abstract: Elevated blood ammonia (hyperammonemia) is believed to be a major contributor to the neurological sequelae following severe liver disease. Ammonia is cleared via two main mechanisms, the urea cycle pathway and the glutamine synthetase reaction.… read more here.
Keywords: glutamine synthetase; ammonia homeostasis; urea cycle; synthetase reaction ... See more keywords
Use Of Quantitative Modelling To Elucidate The Roles Of The Liver, Gut, Kidney, And Muscle In Ammonia Homeostasis And How Lactulose And Rifaximin Alter This Homeostasis
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DOI: 10.2147/ijgm.s218405
Abstract: Abstract Humans must eliminate approximately 1M of ammonia per day while maintaining the blood concentration of this potent neurotoxin at a concentration of only about 30 µM. The mechanisms producing such effective ammonia homeostasis are… read more here.
Keywords: homeostasis; blood; ammonia homeostasis; ammonia ... See more keywords