In Silico Preliminary Association of Ammonia Metabolism Genes GLS, CPS1, and GLUL with Risk of Alzheimer’s Disease, Major Depressive Disorder, and Type 2 Diabetes
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Molecular Neuroscience"
DOI: 10.1007/s12031-018-1035-0
Abstract: Ammonia is a toxic by-product of protein catabolism and is involved in changes in glutamate metabolism. Therefore, ammonia metabolism genes may link a range of diseases involving glutamate signaling such as Alzheimer’s disease (AD), major… read more here.
Keywords: snps; glul; metabolism genes; cps1 ... See more keywords
Combined effects of high salinity and ammonia-N exposure on the energy metabolism, immune response, oxidative resistance and ammonia metabolism of the Pacific white shrimp Litopenaeus vannamei
Sign Up to like & getrecommendations! Published in 2021 at "Aquaculture Reports"
DOI: 10.1016/j.aqrep.2021.100648
Abstract: Abstract In this study, after 30 days of long-time exposure to high salinity (36‰ and 44‰), we explored the combined effects of high salinity and ammonia nitrogen (15 mg/L ammonia-N) stresses on the energy metabolism,… read more here.
Keywords: exposure; ammonia metabolism; metabolism; high salinity ... See more keywords
Clinical significance of the latency period of abnormal ammonia metabolism in chronic liver disease: Proposal of a new concept
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DOI: 10.1111/hepr.13724
Abstract: The liver is a key organ in regulating metabolism, and chronic liver disease is associated with several metabolic disorders. In the later stages of liver cirrhosis, the urea cycle is impaired, which disrupts of ammonia… read more here.
Keywords: period; abnormal ammonia; ammonia metabolism; liver ... See more keywords
Generation of carbamoyl phosphate synthetase 1 reporter cell lines for the assessment of ammonia metabolism
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Cellular and Molecular Medicine"
DOI: 10.1111/jcmm.13225
Abstract: Both primary hepatocytes and stem cells‐derived hepatocyte‐like cells (HLCs) are major sources for bioartificial liver (BAL). Maintenance of hepatocellular functions and induction of functional maturity of HLCs are critical for BAL's support effect. It remains… read more here.
Keywords: reporter; carbamoyl phosphate; detoxification; ammonia metabolism ... See more keywords
Differential ammonia metabolism and toxicity between avian and mammalian species, and effect of ammonia on skeletal muscle: A comparative review.
Sign Up to like & getrecommendations! Published in 2019 at "Journal of animal physiology and animal nutrition"
DOI: 10.1111/jpn.13080
Abstract: Comparative aspects of ammonia toxicity, specific to liver and skeletal muscle and skeletal muscle metabolism between avian and mammalian species are discussed in the context of models for liver disease and subsequent skeletal muscle wasting.… read more here.
Keywords: skeletal muscle; muscle; ammonia metabolism; mammalian species ... See more keywords