PFKFB4 is critical for the survival of acute monocytic leukemia cells.
Sign Up to like & getrecommendations! Published in 2020 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2020.03.174
Abstract: Acute myeloid leukemia (AML), which is characterized by an overproliferation of blood cells, is divided into several subtypes in adults and children. Of those subtypes, acute monocytic leukemia (M4/M5, AMoL) is reported to be associated… read more here.
Keywords: acute monocytic; amol; pfkfb4 critical; monocytic leukemia ... See more keywords
Allograft inflammatory factor -1 is essential for acute monocytic leukemia infiltration
Sign Up to like & getrecommendations! Published in 2025 at "Blood"
DOI: 10.1182/blood-2025-5255
Abstract: Extramedullary infiltration (EMI) is a major cause of treatment failure and relapse in acute myeloid leukemia (AML), particularly in monocytic subtypes (FAB-M4/M5). However, the molecular mechanisms underlying EMI remain incompletely understood. Using public AML data… read more here.
Keywords: aif; aml; leukemia; infiltration ... See more keywords