Evaluation of a Multivalent Transcriptomic Metric for Diagnosing Surgical Sepsis and Estimating Mortality Among Critically Ill Patients
Sign Up to like & getrecommendations! Published in 2022 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2022.21520
Abstract: Key Points Question Can a whole-blood RNA transcriptomic metric (IMX) obtained in the first 12 hours after intensive care unit (ICU) admission accurately measure the presence of bacterial infection and risk for sepsis mortality? Findings… read more here.
Keywords: sepsis; critically ill; transcriptomic metric; mortality ... See more keywords
Abnormal shock index exposure and clinical outcomes among critically ill patients: A retrospective cohort analysis.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of critical care"
DOI: 10.1016/j.jcrc.2020.01.024
Abstract: PURPOSE To assess the predictive value of a single abnormal shock index reading (SI ≥0.9; heart rate/systolic blood pressure [SBP]) for mortality, and association between cumulative abnormal SI exposure and mortality/morbidity. MATERIALS AND METHODS Cohort… read more here.
Keywords: among critically; exposure; shock index; mortality ... See more keywords
Factors associated with beyond-therapeutic serum voriconazole trough level among critically ill patients with invasive fungal infections.
Sign Up to like & getrecommendations! Published in 2025 at "BMC infectious diseases"
DOI: 10.1186/s12879-025-12221-6
Abstract: Various kinds of clinical characteristics predispose patients receiving voriconazole therapy to high variability of serum voriconazole level. However, little is known about the predictors of drug level variability among critically ill patients. This retrospective study… read more here.
Keywords: serum voriconazole; beyond therapeutic; level; among critically ... See more keywords
Major psychiatric comorbidity among the critically ill: a multi-centred cohort study in Queensland
Sign Up to like & getrecommendations! Published in 2025 at "BMC Psychiatry"
DOI: 10.1186/s12888-025-06520-0
Abstract: Although comorbid medical diseases are important determinants of outcome among the critically ill, the role of psychiatric comorbidity is not well defined. The objective of this study was to determine the occurrence of psychiatric comorbidity… read more here.
Keywords: comorbidity; major psychiatric; psychiatric comorbidity; among critically ... See more keywords
Acute kidney injury among critically ill neonates in a tertiary hospital in Tanzania; Prevalence, risk factors and outcome
Sign Up to like & getrecommendations! Published in 2020 at "PLoS ONE"
DOI: 10.1371/journal.pone.0229074
Abstract: Background Neonatal acute kidney injury contributes to high mortality in developing countries. The burden of neonatal AKI is not known in Tanzania despite having high neonatal mortality. This study was conducted to determine the burden… read more here.
Keywords: kidney injury; among critically; acute kidney; critically ill ... See more keywords
Hispanic ethnicity and mortality among critically ill patients with COVID-19
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0268022
Abstract: Background Hispanic persons living in the United States (U.S.) are at higher risk of infection and death from coronavirus disease 2019 (COVID-19) compared with non-Hispanic persons. Whether this disparity exists among critically ill patients with… read more here.
Keywords: ill patients; critically ill; hispanic white; among critically ... See more keywords
Goals of care discussions among critically Ill patients on vasopressor treatment
Sign Up to like & getrecommendations! Published in 2025 at "PLOS One"
DOI: 10.1371/journal.pone.0324482
Abstract: Background Goals of care (GOC) discussions are essential for aligning medical management with the values of critically ill patients, particularly those requiring vasopressors, such as dopamine. To evaluate GOC discussions in terms of prevalence, factors… read more here.
Keywords: goals care; ill patients; goc discussions; among critically ... See more keywords
Impact of obesity on all-cause and cause-specific mortality among critically ill men and women: a cohort study on the eICU database
Sign Up to like & getrecommendations! Published in 2023 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2023.1143404
Abstract: Background The effect of obesity on intensive care unit outcomes among critically ill patients and whether there are sex differences have not been well investigated. We sought to determine the association between obesity and 30-day… read more here.
Keywords: critically ill; cause; men women; mortality ... See more keywords
COVID-19 Disease and Outcomes among Critically Ill Patients: The Case of Medical Nutritional Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Nutrients"
DOI: 10.3390/nu14071416
Abstract: The recent COVID-19 pandemic, which resulted from SARS CoV-2 coronavirus infection, contributed toa rapid increasein hospital and intensive care unit (ICU) admissions [...] read more here.
Keywords: disease outcomes; ill patients; among critically; critically ill ... See more keywords
A High Distribution of Resistant Pathogens among Critically Ill Neonates from Secondary Referral Hospital of Indonesia
Sign Up to like & getrecommendations! Published in 2021 at "Ethiopian Journal of Health Sciences"
DOI: 10.4314/ejhs.v31i3.6
Abstract: Background The spread of resistant pathogens among critically ill neonates has increased in recent years. Therefore, information about the antimicrobial profile and its susceptibility over time helps to select the most appropriate therapy. The study… read more here.
Keywords: susceptibility; pathogens among; among critically; critically ill ... See more keywords