Low-temperature investigations of ion-induced amorphisation in silicon carbide nanowhiskers under helium irradiation
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DOI: 10.1016/j.apsusc.2019.143969
Abstract: Abstract The abundant free surface in nanoporous materials may play a major role in providing ideal sinks for the removal of radiation-induced defects. To study the response of these materials to radiation damage, 4H-silicon carbide… read more here.
Keywords: silicon carbide; irradiation; temperature; amorphisation ... See more keywords
Drug amorphisation by fluid bed hot-melt impregnation of mesoporous silica carriers
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DOI: 10.1016/j.cej.2019.123754
Abstract: Abstract Amorphisation using mesoporous inorganic carriers represents an emerging formulation strategy for the dissolution rate enhancement of poorly water-soluble Active Pharmaceutical Ingredients (APIs). This approach employs API loading to a porous carrier, which stabilises the… read more here.
Keywords: drug amorphisation; amorphisation; silica; drug ... See more keywords
Melt Amorphisation of Orlistat with Mesoporous Silica Using a Supercritical Carbon Dioxide: Effects of Pressure, Temperature, and Drug Loading Ratio and Comparison with Other Conventional Amorphisation Methods
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DOI: 10.3390/pharmaceutics12040377
Abstract: The aim of this work was to develop an amorphous orlistat-loaded mesoporus silica formulation using the melt-amorphisation by supercritical fluid (MA-SCF) and to investigate the effects of pressure and temperature on the pharmaceutical properties of… read more here.
Keywords: conventional amorphisation; amorphisation; silica; amorphisation methods ... See more keywords