Co‐former selection for co‐amorphous drug‐amino acid formulations
Sign Up to like & getrecommendations! Published in 2019 at "International Journal of Pharmaceutics"
DOI: 10.1016/j.ijpharm.2018.12.036
Abstract: Graphical abstract Figure. No Caption available. ABSTRACT We have previously developed a fast screening method on the ability of twenty amino acids (AA) to form co‐amorphous formulations with six drugs upon ball milling. In this… read more here.
Keywords: amino; amorphous formulations; amorphous drug; stability ... See more keywords
Dissolution and permeability properties of co-amorphous formulations of hydrochlorothiazide.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of pharmaceutical sciences"
DOI: 10.1016/j.xphs.2020.04.008
Abstract: A biopharmaceutics classification system class IV drug, hydrochlorothiazide (HCT), was combined with co-formers of L-and D-arginine (ARG) and sodium lauryl sulphate (SLS) by cryomilling in 1:1 molar ratio. Co-amorphization was observed with L- and D-ARG.… read more here.
Keywords: permeability properties; amorphous formulations; permeability; properties amorphous ... See more keywords