RND Pump-Mediated Efflux of Amotosalen, a Compound Used in Pathogen Inactivation Technology to Enhance Safety of Blood Transfusion Products, May Compromise Its Gram-Negative Anti-Bacterial Activity
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DOI: 10.1128/msphere.00673-22
Abstract: Pathogen inactivation is a strategy to enhance the safety of transfused blood products. We identify the compound, amotosalen, widely used for pathogen inactivation, as a bacterial multidrug efflux substrate. ABSTRACT Pathogen inactivation is a strategy… read more here.
Keywords: safety; amotosalen; blood; pathogen inactivation ... See more keywords