AMP‐activated protein kinase is a key regulator of obesity‐associated factors
Sign Up to like & getrecommendations! Published in 2022 at "Cell Biochemistry and Function"
DOI: 10.1002/cbf.3767
Abstract: An imbalance between caloric intake and energy expenditure leads to obesity. Obesity is an important risk factor for the development of several metabolic diseases including insulin resistance, metabolic syndrome, type 2 diabetes mellitus, and cardiovascular… read more here.
Keywords: protein kinase; amp activated; activated protein; associated factors ... See more keywords
Geniposide protects pancreatic β cells from high glucose‐mediated injury by activation of AMP‐activated protein kinase
Sign Up to like & getrecommendations! Published in 2017 at "Cell Biology International"
DOI: 10.1002/cbin.10758
Abstract: Our previous works indicated that geniposide could regulate glucose‐stimulated insulin secretion (GSIS), and improved chronic high glucose‐induced dysfunctions in pancreatic β cells, but the molecular mechanisms remain largely unknown. In the present study, we investigated… read more here.
Keywords: activated protein; high glucose; pancreatic cells; injury ... See more keywords
Aldehyde dehydrogenase‐2 (ALDH2) opposes hepatocellular carcinoma progression by regulating AMP‐activated protein kinase signaling in mice
Sign Up to like & getrecommendations! Published in 2017 at "Hepatology"
DOI: 10.1002/hep.29006
Abstract: Potential biomarkers that can be used to determine prognosis and perform targeted therapies are urgently needed to treat patients with hepatocellular carcinoma (HCC). To meet this need, we performed a screen to identify functional genes… read more here.
Keywords: protein; hepatocellular carcinoma; hcc; amp activated ... See more keywords
Perilaldehyde activates AMP‐activated protein kinase to suppress the growth of gastric cancer via induction of autophagy
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Cellular Biochemistry"
DOI: 10.1002/jcb.27491
Abstract: Background and Aim: Perillaldehyde (PAH), one of the major oil components in Perilla frutescens, is very critical to health maintenance, for a wide range of human chronic diseases, including cancers. AMP‐activated protein kinase (AMPK) has… read more here.
Keywords: gastric cancer; activated protein; autophagy; protein kinase ... See more keywords
AMP‐activated protein kinase inhibition in fibro‐adipogenic progenitors impairs muscle regeneration and increases fibrosis
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Cachexia, Sarcopenia and Muscle"
DOI: 10.1002/jcsm.13150
Abstract: Following muscle injury, fibro‐adipogenic progenitors (FAPs) are rapidly activated and undergo apoptosis at the resolution stage, which is required for proper muscle regeneration. When excessive FAPs remain, it contributes to fibrotic and fatty infiltration, impairing… read more here.
Keywords: amp activated; fibro adipogenic; muscle; muscle regeneration ... See more keywords
Dietary apple polyphenols promote fat browning in high-fat diet-induced obese mice through activation of AMP-activated protein kinase (AMPK) α.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the science of food and agriculture"
DOI: 10.1002/jsfa.10248
Abstract: BACKGROUND Promoting brown and beige adipogenesis contributes to adaptive thermogenesis, which provides a defense against obesity and related disorders. Apple polyphenols (APs) play a significant role in treating variety of metabolic diseases. The present study… read more here.
Keywords: obese mice; apple polyphenols; activated protein; protein kinase ... See more keywords
Cryoprotective effect of resveratrol on DNA damage and crucial human sperm messenger RNAs, possibly through 5′ AMP-activated protein kinase activation
Sign Up to like & getrecommendations! Published in 2017 at "Cell and Tissue Banking"
DOI: 10.1007/s10561-017-9642-5
Abstract: This work aimed at investigating the effect of resveratrol on (1) DNA integrity and (2) fertilizing capacity of sperm by quantifying the presence of key paternal transcripts considered as markers for male fertility (protamine 1… read more here.
Keywords: dna; effect resveratrol; resveratrol dna; effect ... See more keywords
Activation of AMP-Activated Protein Kinases Prevents Atrial Fibrillation
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Cardiovascular Translational Research"
DOI: 10.1007/s12265-020-10069-6
Abstract: Atrial fibrillation (AF) is common, yet there is no preventive therapy for AF. We tested the efficacy of AMP-activated protein kinase (AMPK) activators, metformin, and aspirin, in primary prevention of AF in cardiac-specific liver kinase… read more here.
Keywords: atrial fibrillation; activated protein; treated mice; activation ... See more keywords
AMP-Activated Protein Kinase
Sign Up to like & getrecommendations! Published in 2017 at "Circulation Research"
DOI: 10.1016/b978-0-12-374145-5.00073-5
Abstract: The AMP-activated protein kinase (AMPK) is a key regulator of cellular and whole-body energy homeostasis, which acts to restore energy homoeostasis whenever cellular energy charge is depleted. Over... read more here.
Keywords: energy; protein kinase; amp activated; activated protein ... See more keywords
Regulation of podocytes function by AMP-activated protein kinase.
Sign Up to like & getrecommendations! Published in 2020 at "Archives of biochemistry and biophysics"
DOI: 10.1016/j.abb.2020.108541
Abstract: Podocytes are unique, highly specialized, terminally differentiated cells that form an essential, integral part of the glomerular filter. These cells limit the outside border of the glomerular basement membrane, forming a tight barrier that prevents… read more here.
Keywords: activated protein; protein kinase; function; amp activated ... See more keywords
AMP-activated protein kinase stabilizes FOXO3 in primary myotubes.
Sign Up to like & getrecommendations! Published in 2018 at "Biochemical and biophysical research communications"
DOI: 10.1016/j.bbrc.2018.03.176
Abstract: AMP-activated protein kinase (AMPK) is a critical enzyme in conditions of cellular energy deficit such as exercise, hypoxia or nutritional stress. AMPK is well known to regulate protein degradation pathways notably through FOXO-related axis. In… read more here.
Keywords: activated protein; stabilizes foxo3; primary myotubes; protein kinase ... See more keywords