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Second Messenger 2'3'-cyclic GMP-AMP (2'3'-cGAMP):Synthesis, transmission, and degradation.

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Published in 2022 at "Biochemical pharmacology"

DOI: 10.1016/j.bcp.2022.114934

Abstract: Cyclic GMP-AMP synthase (cGAS) senses foreign DNA to produce 2'3'-cyclic GMP-AMP (2'3'-cGAMP). 2'3'-cGAMP is a second messenger that binds and activates the adaptor protein STING, which triggers the innate immune response. As a STING agonist,… read more here.

Keywords: cgamp; amp cgamp; gmp amp; cyclic gmp ... See more keywords