Genetic manipulations of AMPA glutamate receptors in hippocampal synaptic plasticity
Sign Up to like & getrecommendations! Published in 2021 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2021.108630
Abstract: Alpha-amino-3-hydroxy-5-methyl-4-isoxazolepropionic acid receptors (AMPARs) are the principal mediators of fast excitatory synaptic transmission and they are required for various forms of synaptic plasticity, including long-term potentiation (LTP) and depression (LTD), which are key mechanisms of… read more here.
Keywords: ampa glutamate; manipulations ampa; synaptic plasticity; glutamate receptors ... See more keywords
Gating and modulation of a hetero-octameric AMPA glutamate receptor.
Sign Up to like & getrecommendations! Published in 2021 at "Nature"
DOI: 10.1038/s41586-021-03613-0
Abstract: AMPA receptors (AMPARs) mediate the majority of excitatory transmission in the brain and enable the synaptic plasticity that underlies learning1. A diverse array of AMPAR signalling complexes are established by receptor auxiliary subunits, which associate… read more here.
Keywords: hetero octameric; ampa glutamate; gating modulation; receptor ... See more keywords