Facilitated AMPAR endocytosis causally contributes to the maternal sleep deprivation-induced impairments of synaptic plasticity and cognition in the offspring rats
Sign Up to like & getrecommendations! Published in 2018 at "Neuropharmacology"
DOI: 10.1016/j.neuropharm.2018.01.030
Abstract: ABSTRACT Maternal sleep deprivation (MSD) has been suggested to be associated with increased frequency of neurodevelopmental disorders in offspring in both humans and animal models. However, the underlying cellular and molecular mechanism is still unclear.… read more here.
Keywords: sleep deprivation; ampar endocytosis; offspring rats; maternal sleep ... See more keywords
Endophilin2 Interacts with GluA1 to Mediate AMPA Receptor Endocytosis Induced by Oligomeric Amyloid-β
Sign Up to like & getrecommendations! Published in 2017 at "Neural Plasticity"
DOI: 10.1155/2017/8197085
Abstract: Amyloid-β (Aβ) plays an important role in Alzheimer's disease (AD), as oligomeric Aβ induces loss of postsynaptic AMPA receptors (AMPARs) leading to cognitive deficits. The loss of postsynaptic AMPARs is mediated through the clathrin-dependent endocytosis… read more here.
Keywords: endocytosis; ampar endocytosis; oligomeric induced; endophilin2 interacts ... See more keywords