Machine Learning and Deep Learning Models for Predicting Noncovalent Inhibitors of AmpC β-Lactamase
Sign Up to like & getrecommendations! Published in 2024 at "ACS Omega"
DOI: 10.1021/acsomega.4c03834
Abstract: Continuous use of antibiotics leads to the ability of bacteria to adapt by developing complex antibiotic resistance (AR) mechanisms. The synthesis of β-lactamases is a widely observed AR mechanism. The class C β-lactamase (AmpC) causes… read more here.
Keywords: inhibitors ampc; models predicting; machine; noncovalent inhibitors ... See more keywords
Multiplex PCR to detect pAmpC β-lactamases among enterobacteriaceae at a tertiary care laboratory in Mumbai, India.
Sign Up to like & getrecommendations! Published in 2019 at "Microbiology"
DOI: 10.1099/mic.0.000748
Abstract: Drug-resistance due to AmpC β-lactamases represents a growing problem worldwide. In this study, a previously collected sample of 108 cefoxitin-resistant clinical isolates was assessed for AmpC β-lactamase production through routine phenotypic testing and double-disc cefoxitin/cloxcallin… read more here.
Keywords: ampc lactamase; lactamase producers; blaact; pcr detect ... See more keywords
Comparison of Ceftriaxone and Antipseudomonal β-Lactam Antibiotics Utilized for Potential AmpC β-Lactamase-Producing Organisms
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DOI: 10.1177/0018578720931463
Abstract: Background: Induction of antibiotic resistance is associated with increased morbidity and mortality in AmpC β-lactamase producing Enterobacteriaceae. The use of ceftriaxone is controversial for tre... read more here.
Keywords: ampc lactamase; antipseudomonal lactam; ceftriaxone antipseudomonal; comparison ceftriaxone ... See more keywords
Prevalence and molecular characteristics of ESBL and AmpC β -lactamase producing Enterobacteriaceae strains isolated from UTIs in Egypt
Sign Up to like & getrecommendations! Published in 2020 at "Antimicrobial Resistance and Infection Control"
DOI: 10.1186/s13756-020-00856-w
Abstract: Background Infections caused by Enterobacteriaceae are mainly treated with the β-lactam antibiotics, nevertheless, the emergence of species with plasmid-borne β-lactamases has decreased the efficacy of these antibiotics. Therefore, continuing studies on the resistance pattern of… read more here.
Keywords: ampc lactamase; producing enterobacteriaceae; esbl; esbl producers ... See more keywords
Frequency of extended-spectrum β-lactamase (ESBL)- and AmpC β-lactamase-producing Enterobacteriaceae in a cheese production process.
Sign Up to like & getrecommendations! Published in 2018 at "Journal of dairy science"
DOI: 10.3168/jds.2017-13878
Abstract: The aim of this study was to investigate the extended-spectrum β-lactamase (ESBL) and AmpC β-lactamase activities of Enterobacteriaceae isolated from raw milk and cheese production line and to determine the probability of transmitting these bacteria… read more here.
Keywords: ampc lactamase; cheese production; esbl ampc; lactamase ... See more keywords
Characterization of a Novel Chromosome-Encoded AmpC β-Lactamase Gene, blaPRC–1, in an Isolate of a Newly Classified Pseudomonas Species, Pseudomonas wenzhouensis A20, From Animal Farm Sewage
Sign Up to like & getrecommendations! Published in 2021 at "Frontiers in Microbiology"
DOI: 10.3389/fmicb.2021.732932
Abstract: In this work, we characterized a novel chromosome-encoded AmpC β-lactamase gene, blaPRC–1, in an isolate of a newly classified Pseudomonas species designated Pseudomonas wenzhouensis A20, which was isolated from sewage discharged from an animal farm… read more here.
Keywords: ampc lactamase; chromosome encoded; novel chromosome; gene ... See more keywords
Molecular detection of plasmid-derived AmpC β-lactamase among clinical strains of Enterobacteriaceae in Bahrain
Sign Up to like & getrecommendations! Published in 2021 at "Annals of Thoracic Medicine"
DOI: 10.4103/atm.atm_523_20
Abstract: BACKGROUND: Enterobacteriaceae with AmpC β-lactamase are multidrug-resistant organisms and represent a significant challenge to patient care. This study aims to determine the prevalence of plasmid-derived AmpC β-lactamase among extended spectrum β-lactamases (ESBL)-producing Enterobacteriaceae strains in… read more here.
Keywords: among clinical; derived ampc; plasmid derived; ampc lactamase ... See more keywords