Assessment of amphiphilic poly-N-vinylpyrrolidone nanoparticles' biocompatibility with endothelial cells in vitro and delivery of anti-inflammatory drug.
Sign Up to like & getrecommendations! Published in 2020 at "Molecular pharmaceutics"
DOI: 10.1021/acs.molpharmaceut.0c00667
Abstract: Nanoparticles (NPs) produced from amphiphilic derivatives of poly-N-vinylpyrrolidone (Amph-PVP), composed of various molecular weight polymeric hydrophilic fragments and linked into hydrophobic n-alkyl chains of varying lengths were previously shown to exert excellent biocompatibility. Although routes… read more here.
Keywords: pvp nps; drug; endothelial cells; amph pvp ... See more keywords
Amphiphilic Poly(N-vinylpyrrolidone) Nanoparticles Conjugated with DR5-Specific Antitumor Cytokine DR5-B for Targeted Delivery to Cancer Cells
Sign Up to like & getrecommendations! Published in 2021 at "Pharmaceutics"
DOI: 10.3390/pharmaceutics13091413
Abstract: Nanoparticles based on the biocompatible amphiphilic poly(N-vinylpyrrolidone) (Amph-PVP) derivatives are promising for drug delivery. Amph-PVPs self-aggregate in aqueous solutions with the formation of micellar nanoscaled structures. Amph-PVP nanoparticles are able to immobilize therapeutic molecules under… read more here.
Keywords: delivery; amph pvp; dr5; antitumor ... See more keywords