Articles with "ampk 06409577" as a keyword



Photo by nci from unsplash

Activation of Liver AMPK with PF-06409577 Corrects NAFLD and Lowers Cholesterol in Rodent and Primate Preclinical Models

Sign Up to like & get
recommendations!
Published in 2018 at "EBioMedicine"

DOI: 10.1016/j.ebiom.2018.04.009

Abstract: Dysregulation of hepatic lipid and cholesterol metabolism is a significant contributor to cardiometabolic health, resulting in excessive liver lipid accumulation and ultimately non-alcoholic steatohepatitis (NASH). Therapeutic activators of the AMP-Activated Protein Kinase (AMPK) have been… read more here.

Keywords: liver ampk; cholesterol; lipid cholesterol; ampk 06409577 ... See more keywords