Neuronal ablation of GHSR mitigates diet-induced depression and memory impairment via AMPK-autophagy signaling-mediated inflammation
Sign Up to like & getrecommendations! Published in 2024 at "Frontiers in Immunology"
DOI: 10.3389/fimmu.2024.1339937
Abstract: Obesity is associated with chronic inflammation in the central nervous system (CNS), and neuroinflammation has been shown to have detrimental effects on mood and cognition. The growth hormone secretagogue receptor (GHSR), the biologically relevant receptor… read more here.
Keywords: ghsr; neuronal ghsr; diet induced; autophagy signaling ... See more keywords
Role of AMPK in autophagy
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Physiology"
DOI: 10.3389/fphys.2022.1015500
Abstract: Adenosine monophosphate-activated protein kinase (AMPK) is a significant energy sensor in the maintenance of cellular energy homeostasis. Autophagy is a highly conserved catabolic process that involves an intracellular degradation system in which cytoplasmic components, such… read more here.
Keywords: role ampk; ampk autophagy; ampk; process ... See more keywords
Co-Expression Network Analysis of AMPK and Autophagy Gene Products during Adipocyte Differentiation
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DOI: 10.3390/ijms19061808
Abstract: Autophagy is involved in the development and differentiation of many cell types. It is essential for the pre-adipocytes to respond to the differentiation stimuli and may contribute to reorganizing the intracellulum to adapt the morphological… read more here.
Keywords: ampk autophagy; adipocyte differentiation; autophagy gene; gene products ... See more keywords