Metformin effectively treats Tsc1 deletion-caused kidney pathology by upregulating AMPK phosphorylation
Sign Up to like & getrecommendations! Published in 2020 at "Cell Death Discovery"
DOI: 10.1038/s41420-020-0285-0
Abstract: Tuberous sclerosis complex (TSC) is characterized by hamartomatous lesions in multiple organs, with most patients developing polycystic kidney disease and leading to a decline of renal function. TSC is caused by loss-of-function mutations in either… read more here.
Keywords: ampk phosphorylation; metformin; pathology; tsc1 deletion ... See more keywords
Metabolic Impact of Light Phase-Restricted Fructose Consumption Is Linked to Changes in Hypothalamic AMPK Phosphorylation and Melatonin Production in Rats
Sign Up to like & getrecommendations! Published in 2017 at "Nutrients"
DOI: 10.3390/nu9040332
Abstract: Recent studies show that the metabolic effects of fructose may vary depending on the phase of its consumption along with the light/dark cycle. Here, we investigated the metabolic outcomes of fructose consumption by rats during… read more here.
Keywords: light phase; phase; hypothalamic ampk; ampk phosphorylation ... See more keywords