AMPK is not required for the effect of metformin on the inhibition of BMP6-induced hepcidin gene expression in hepatocytes
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DOI: 10.1038/s41598-017-12976-2
Abstract: The biguanide metformin is used for its antidiabetic effect for many years but how metformin acts remains poorly understood and controversial. AMP-activated protein kinase (AMPK), a protein kinase that plays a key role in maintaining… read more here.
Keywords: metformin; hepcidin gene; induced hepcidin; expression ... See more keywords
AMPK is required for recovery from metabolic stress induced by ultrasound microbubble treatment
Sign Up to like & getrecommendations! Published in 2022 at "iScience"
DOI: 10.1101/2022.03.02.482704
Abstract: Ultrasound and microbubbles (USMB) is a promising strategy for cancer therapy. USMB can induce a variety of effects on cells including transient formation of plasma membrane pores (sonoporation) and enhanced endocytosis, which enhance drug delivery,… read more here.
Keywords: ampk required; stress; usmb treatment; required recovery ... See more keywords