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   Articles with "ampk signaling" as a keyword



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CCAL1 enhances osteoarthritis through the NF‐κB/AMPK signaling pathway

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recommendations! Published in 2020 at "FEBS Open Bio"

DOI: 10.1002/2211-5463.12989

Abstract: Osteoarthritis (OA) is a chronic joint disease characterized by articular cartilage degeneration and secondary osteogenesis. It has been previously demonstrated that the CCAL1 locus is the gene encoding tumor necrosis factor receptor superfamily member 11B… read more here.

Keywords: signaling pathway; enhances osteoarthritis; ccal1 enhances; ampk signaling ... See more keywords
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Neuroprotection of melatonin on spinal cord injury by activating autophagy and inhibiting apoptosis via SIRT1/AMPK signaling pathway

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recommendations! Published in 2020 at "Biotechnology Letters"

DOI: 10.1007/s10529-020-02939-5

Abstract: The effect of melatonin (MT) on spinal cord injury (SCI) has attracted increasing research attention. However, the specific role and molecular mechanism of MT on SCI have not been elucidated. An experiment was performed to… read more here.

Keywords: sci; sirt1 ampk; spinal cord; signaling pathway ... See more keywords
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MiR-3682 promotes the progression of hepatocellular carcinoma (HCC) via inactivating AMPK signaling by targeting ADRA1A.

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recommendations! Published in 2021 at "Annals of hepatology"

DOI: 10.1016/j.aohep.2021.100570

Abstract: INTRODUCTION AND OBJECTIVES This study aimed to investigate miR-3682 as a biomarker in hepatocellular carcinoma (HCC)1. MATERIALS AND METHODS MiRNA and RNA profiles of 375 HCC tissues and 50 normal liver samples were downloaded from… read more here.

Keywords: hepatocellular carcinoma; hcc; carcinoma hcc; mir 3682 ... See more keywords
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AntogomiR-451 protects human gastric epithelial cells from ethanol via activating AMPK signaling.

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recommendations! Published in 2018 at "Biochemical and biophysical research communications"

DOI: 10.1016/j.bbrc.2018.02.082

Abstract: The prevention and treatment efficiency of ethanol-induced gastric epithelial injury are not satisfied. We have previously shown that AMP-activated protein kinase (AMPK) activation exerts a pro-survival function in human gastric epithelial cells (GECs). miroRNA-451 ("miR-451")'s… read more here.

Keywords: gastric epithelial; epithelial cells; antagomir 451; ampk activation ... See more keywords
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3,6-Anhydro-L-galactose increases hyaluronic acid production via the EGFR and AMPKα signaling pathway in HaCaT keratinocytes.

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recommendations! Published in 2019 at "Journal of dermatological science"

DOI: 10.1016/j.jdermsci.2019.10.005

Abstract: BACKGROUND Hyaluronic acid (HA) is an important factor in skin hydration maintenance. In mammalian keratinocytes, hyaluronan synthase 2 (HAS2) is a critical enzyme in HA production. Therefore, the promotion of HAS2 expression in keratinocytes may… read more here.

Keywords: production; has2 expression; anhydro galactose; signaling pathway ... See more keywords
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Resveratrol protects against spinal cord injury by activating autophagy and inhibiting apoptosis mediated by the SIRT1/AMPK signaling pathway

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recommendations! Published in 2017 at "Neuroscience"

DOI: 10.1016/j.neuroscience.2017.02.027

Abstract: Spinal cord injury (SCI) is a devastating condition with few effective treatments. Resveratrol, a polyphenolic compound, has exhibited neuroprotective effects in many neurodegenerative diseases. However, the explicit effect and mechanism of resveratrol on SCI is… read more here.

Keywords: resveratrol; sirt1 ampk; spinal cord; ampk ... See more keywords
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Acetate Stimulates Lipogenesis via AMPKα Signaling in Rabbit Adipose-derived Stem Cells.

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recommendations! Published in 2021 at "General and comparative endocrinology"

DOI: 10.1016/j.ygcen.2021.113715

Abstract: Acetate plays an important role in host lipid metabolism. However, the regulatory network underlying acetate-regulated lipometabolism remains unclear. The aim of this study was to determine whether any cross talk occurs among adenosine 5'-monophosphate-activated protein… read more here.

Keywords: acetate; ampk; rabbit adipose; adipose derived ... See more keywords
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Nuciferine Ameliorates Nonesterified Fatty Acid-Induced Bovine Mammary Epithelial Cell Lipid Accumulation, Apoptosis, and Impaired Migration via Activating LKB1/AMPK Signaling Pathway.

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recommendations! Published in 2022 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c06133

Abstract: High blood concentrations of nonesterified fatty acids (NEFAs) provoke various metabolic disorders and are associated with mammary tissue injury and decreased milk production in dairy cows. Nuciferine, an alkaloid found in Nelumbo nucifera leaves, has… read more here.

Keywords: lipid accumulation; ampk; migration; accumulation apoptosis ... See more keywords
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Intracellular Calcium Overload and Activation of CaMKK/AMPK Signaling Are Related to the Acceleration of Muscle Glycolysis of Broiler Chickens Subjected to Acute Stress.

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recommendations! Published in 2023 at "Journal of agricultural and food chemistry"

DOI: 10.1021/acs.jafc.2c07391

Abstract: The current study investigated the effect of preslaughter transport on stress response and meat quality of broilers and explored the underlying mechanisms involved in the regulation of muscle glycolysis through calcium/calmodulin-dependent protein kinase kinase (CaMKK)/AMP-activated… read more here.

Keywords: stress; calcium; muscle glycolysis; camkk ... See more keywords
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2-deoxyglucose transiently inhibits yeast AMPK signaling and triggers glucose transporter endocytosis, potentiating the drug toxicity

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recommendations! Published in 2022 at "PLoS Genetics"

DOI: 10.1101/2022.03.29.486183

Abstract: 2-deoxyglucose is a glucose analog that impacts many aspects of cellular physiology. After its uptake and its phosphorylation into 2-deoxyglucose-6-phosphate (2DG6P), it interferes with several metabolic pathways including glycolysis and protein N-glycosylation. Despite this systemic… read more here.

Keywords: glucose transporter; resistance; transporter endocytosis; endocytosis ... See more keywords
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miR-451 on Myocardial Ischemia-Reperfusion in Rats by Regulating AMPK Signaling Pathway

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recommendations! Published in 2021 at "BioMed Research International"

DOI: 10.1155/2021/9933998

Abstract: Myocardial infarction is the main cause of death in patients with coronary heart disease. At present, the main method to treat cardiovascular disease is perfusion therapy. Myocardial ischemia-reperfusion will inevitably lead to reperfusion injury, which… read more here.

Keywords: myocardial ischemia; reperfusion; mir 451; ischemia reperfusion ... See more keywords