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   Articles with "ampk sirt" as a keyword



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Liraglutide induces beige fat development and promotes mitochondrial function in diet induced obesity mice partially through AMPK-SIRT-1-PGC1-α cell signaling pathway

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recommendations! Published in 2018 at "Endocrine"

DOI: 10.1007/s12020-018-1826-7

Abstract: PurposeGlucagon like peptide-1 (GLP-1) is produced to induce postprandial insulin secretion. Liraglutide, a full agonist of the GLP-1 receptor, has a protective effect on weight gain in obese subjects. Brown adipose tissue plays a major… read more here.

Keywords: cell signaling; ampk sirt; obesity; cell ... See more keywords
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Empagliflozin attenuates doxorubicin-induced cardiotoxicity by activating AMPK/SIRT-1/PGC-1α-mediated mitochondrial biogenesis

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recommendations! Published in 2023 at "Toxicology Research"

DOI: 10.1093/toxres/tfad007

Abstract: Abstract We aimed to probe the functions and possible mechanisms of empagliflozin in doxorubicin (Dox)-caused cardiotoxicity. First, a cardiotoxicity rat model was built by continuously injecting Dox intraperitoneally. Then, empagliflozin (30 mg/kg) was gavaged into… read more here.

Keywords: ampk sirt; sirt pgc; dox; cardiotoxicity ... See more keywords
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Effect of Empagliflozin on Thioacetamide-Induced Liver Injury in Rats: Role of AMPK/SIRT-1/HIF-1α Pathway in Halting Liver Fibrosis

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recommendations! Published in 2022 at "Antioxidants"

DOI: 10.3390/antiox11112152

Abstract: Hepatic fibrosis causes severe morbidity and death. No viable treatment can repair fibrosis and protect the liver until now. We intended to discover the empagliflozin’s (EMPA) hepatoprotective efficacy in thioacetamide (TAA)-induced hepatotoxicity by targeting AMPK/SIRT-1… read more here.

Keywords: liver fibrosis; effect; hif; ampk sirt ... See more keywords

Fish oil alleviates liver injury induced by intestinal ischemia/reperfusion via AMPK/SIRT-1/autophagy pathway

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recommendations! Published in 2018 at "World Journal of Gastroenterology"

DOI: 10.3748/wjg.v24.i7.833

Abstract: AIM To evaluate whether fish oil (FO) can protect liver injury induced by intestinal ischemia/reperfusion (I/R) via the AMPK/SIRT-1/autophagy pathway. METHODS Ischemia in Wistar rats was induced by superior mesenteric artery occlusion for 60 min… read more here.

Keywords: sirt; reperfusion; sirt autophagy; ampk sirt ... See more keywords