Asperosaponin VI mitigates mitochondrial dysfunction and chondrocyte apoptosis in osteoarthritis by modulating the AMPK-SIRT3 pathway
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DOI: 10.1007/s10565-025-10071-1
Abstract: To investigate the therapeutic potential of Asperosaponin VI (ASA VI) from Clematis chinensis in mitigating osteoarthritis (OA) progression by modulating the AMPK-SIRT3 pathway, specifically addressing ER stress, mitochondrial dysfunction, and chondrocyte apoptosis. In vitro studies… read more here.
Keywords: mitochondrial dysfunction; sirt3 pathway; ampk sirt3; chondrocyte apoptosis ... See more keywords