In Situ Genetically Cascaded Amplification for Imaging RNA Subcellular Locations.
Sign Up to like & getrecommendations! Published in 2020 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.9b11748
Abstract: In situ amplification methods, such as hybridization chain reaction, are valuable tools for mapping the spatial distribution and subcellular location of target analytes. However, the live-cell applications of these methods are still limited due to… read more here.
Keywords: situ genetically; imaging rna; amplification imaging; cascaded amplification ... See more keywords
An azoreductase activatable, endonuclease-gated nanodevice for spatiotemporal amplification imaging of microRNA-21 in hypoxic tumor cells.
Sign Up to like & getrecommendations! Published in 2023 at "Chemical communications"
DOI: 10.1039/d3cc00980g
Abstract: Herein, we report an azoreductase activatable, endonuclease-gated fluorescent nanodevice for spatiotemporal amplification imaging of microRNA-21 in hypoxic tumor cells. We hope that this work can provide a new tool for accurate monitoring of the abundance… read more here.
Keywords: amplification imaging; spatiotemporal amplification; activatable endonuclease; endonuclease gated ... See more keywords