MET gene amplification is a mechanism of resistance to entrectinib in ROS1+ NSCLC
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DOI: 10.1111/1759-7714.14656
Abstract: ROS1 tyrosine kinase inhibitors (TKIs) have demonstrated significant clinical benefit for ROS1+ NSCLC patients. However, TKI resistance inevitably develops through ROS1 kinase domain (KD) modification or another kinase driving bypass signaling. While multiple TKIs have… read more here.
Keywords: amplification mechanism; ros1; ros1 nsclc; met gene ... See more keywords
Actively tuning of transverse wave band gaps in hybrid sandwich beam metamaterials with shunted piezoelectric array and inertial amplification mechanism
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Intelligent Material Systems and Structures"
DOI: 10.1177/1045389x221093547
Abstract: In this paper, a tunable sandwich beam metamaterial is designed by implementing a hybrid project composed of the piezoelectric shunted array technique and the inertial amplification mechanism. Concerned with the shunted piezoelectric constitutive relation, the… read more here.
Keywords: band; amplification mechanism; sandwich beam; inertial amplification ... See more keywords