A simple, sensitive and non-enzymatic signal amplification strategy driven by seesaw gate.
Sign Up to like & getrecommendations! Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.02.029
Abstract: Herein, a simple enzyme-free method based on the seesaw-gate-driven isothermal signal amplification strategy was developed for nucleic acid detection. In this method, a partially complementary double-stranded beacon was designed, after the addition of ssDNA or… read more here.
Keywords: seesaw gate; method; amplification strategy; signal amplification ... See more keywords
Reduced graphene oxide nanosheets and gold nanoparticles covalently linked to ferrocene-terminated dendrimer to construct electrochemical sensor with dual signal amplification strategy for ultra-sensitive detection of pesticide in vegetable
Sign Up to like & getrecommendations! Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.105016
Abstract: Abstract We report herein a novel electrochemical signal amplification strategy for ultra-sensitive detection of pesticide by covalently linking nanoparticles (AuNPs) and reduced graphene oxide (rGO) nanosheets to ferrocene units of ply (amine) ester based ferrocene… read more here.
Keywords: detection; strategy ultra; amplification strategy; signal amplification ... See more keywords
DSN/TdT recycling digestion based cyclic amplification strategy for microRNA assay.
Sign Up to like & getrecommendations! Published in 2020 at "Talanta"
DOI: 10.1016/j.talanta.2020.121173
Abstract: Sensitive and specific detection of microRNAs (miRNAs) is of great significance for early cancer diagnosis. Here we report a simple and sensitive fluorescence signal amplification strategy that based on DSN/TdT recycling digestion for miRNA detection.… read more here.
Keywords: dsn tdt; tdt; amplification strategy; digestion ... See more keywords
Localized Bicirculating DNAzyme Self-Feedback Amplification Strategy for Ultra-Sensitive Fluorescence Biosensing of MicroRNA.
Sign Up to like & getrecommendations! Published in 2025 at "Analytical chemistry"
DOI: 10.1021/acs.analchem.4c04417
Abstract: DNAzyme-based cascade networks are effective tools to achieve ultrasensitive detection of low-abundance miRNAs. However, their designs are complicated and costly, and the operation is time-consuming. Herein, a novel simple noncascade DNAzyme network is designed and… read more here.
Keywords: bicirculating dnazyme; self feedback; amplification strategy; dnazyme ... See more keywords
Glucose Oxidase-Instructed Fluorescence Amplification Strategy for Intracellular Glucose Detection.
Sign Up to like & getrecommendations! Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b00010
Abstract: The accurate detection of glucose at cellular level remains a big challenge. In this study, a signal amplification strategy mediated by silver nanocube (AgNC), glucose oxidase (GOx), and silver ion fluorescence probe (denoted as AgNC-GOx/Ag+-FP)… read more here.
Keywords: detection; fluorescence; intracellular glucose; amplification strategy ... See more keywords
Multiple-Signal Amplification Strategy to Fabricate an Ultrasensitive Electrochemiluminescence Magnetic Immunosensor for Detecting Biomarkers of Alzheimer's Disease via Iridium-Based Self-Enhancing Nanoemitters.
Sign Up to like & getrecommendations! Published in 2025 at "ACS sensors"
DOI: 10.1021/acssensors.4c02916
Abstract: Alzheimer's disease (AD) is characterized by progressive memory loss and cognitive decline, significantly impairing the daily life of elderly individuals. The low abundance of blood-based biomarkers in AD necessitates higher analytical technique requirements. Herein, one… read more here.
Keywords: signal amplification; amplification strategy; iridium based; amplification ... See more keywords
A triple-amplification strategy for sensitive detection of telomerase at the single-cell level.
Sign Up to like & getrecommendations! Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc05100c
Abstract: We develop a triple-amplification strategy for sensitive detection of telomerase from cancer cells using telomere-based primer generation-triggered rolling circle amplification in combination with enzyme-assisted cyclic signal amplification. This method can detect telomerase at the single-cell… read more here.
Keywords: telomerase; triple amplification; strategy sensitive; amplification strategy ... See more keywords
An efficient amplification strategy for N-doped NiCo2O4 with oxygen vacancies and partial Ni/Co-nitrides as a dual-function electrode for both supercapatteries and hydrogen electrocatalysis
Sign Up to like & getrecommendations! Published in 2019 at "Journal of Materials Chemistry A"
DOI: 10.1039/c8ta07210h
Abstract: N-doped NCO electrodes exhibited excellent electrochemical performance for supercapacitors and hydrogen evolution reaction electrocatalysis in KOH electrolyte. read more here.
Keywords: electrocatalysis; efficient amplification; nico2o4 oxygen; doped nico2o4 ... See more keywords
Ultrasensitive fluorescent aptasensor for CRP detection based on the RNase H assisted DNA recycling signal amplification strategy
Sign Up to like & getrecommendations! Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra01352k
Abstract: An aptamer-based method for the ultrasensitive fluorescence detection of C-reactive protein (CRP) was developed using the ribonuclease H (RNase H) assisted DNA recycling signal amplification strategy. read more here.
Keywords: recycling signal; signal amplification; assisted dna; dna recycling ... See more keywords
A novel intracellular signal amplification strategy for the quantification of ATP in single cells by microchip electrophoresis with laser-induced fluorescence detection.
Sign Up to like & getrecommendations! Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc02072a
Abstract: An intracellular signal amplification strategy was developed for the quantification of ATP in single cells by microchip electrophoresis with laser-induced fluorescence detection. By using the method proposed, intracellular ATP levels in single HeLa, HepG2 and… read more here.
Keywords: intracellular signal; atp single; quantification atp; amplification strategy ... See more keywords
Dual amplification strategy turns TRPM2 channels into supersensitive central heat detectors
Sign Up to like & getrecommendations! Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212378119
Abstract: Significance Thermoregulation in the mammalian body is mediated by a central brain thermostat. Because deep-brain temperatures are maintained within a narrow range, the thermostat must contain a sensor that can differentiate temperature fluctuations as small… read more here.
Keywords: strategy turns; amplification strategy; channels supersensitive; dual amplification ... See more keywords