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Published in 2020 at "Analytica chimica acta"
DOI: 10.1016/j.aca.2020.02.029
Abstract: Herein, a simple enzyme-free method based on the seesaw-gate-driven isothermal signal amplification strategy was developed for nucleic acid detection. In this method, a partially complementary double-stranded beacon was designed, after the addition of ssDNA or… read more here.
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Published in 2020 at "Microchemical Journal"
DOI: 10.1016/j.microc.2020.105016
Abstract: Abstract We report herein a novel electrochemical signal amplification strategy for ultra-sensitive detection of pesticide by covalently linking nanoparticles (AuNPs) and reduced graphene oxide (rGO) nanosheets to ferrocene units of ply (amine) ester based ferrocene… read more here.
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Published in 2020 at "Talanta"
DOI: 10.1016/j.talanta.2020.121173
Abstract: Sensitive and specific detection of microRNAs (miRNAs) is of great significance for early cancer diagnosis. Here we report a simple and sensitive fluorescence signal amplification strategy that based on DSN/TdT recycling digestion for miRNA detection.… read more here.
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Published in 2019 at "ACS applied materials & interfaces"
DOI: 10.1021/acsami.9b00010
Abstract: The accurate detection of glucose at cellular level remains a big challenge. In this study, a signal amplification strategy mediated by silver nanocube (AgNC), glucose oxidase (GOx), and silver ion fluorescence probe (denoted as AgNC-GOx/Ag+-FP)… read more here.
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Published in 2018 at "Chemical communications"
DOI: 10.1039/c8cc05100c
Abstract: We develop a triple-amplification strategy for sensitive detection of telomerase from cancer cells using telomere-based primer generation-triggered rolling circle amplification in combination with enzyme-assisted cyclic signal amplification. This method can detect telomerase at the single-cell… read more here.
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Published in 2019 at "RSC Advances"
DOI: 10.1039/c9ra01352k
Abstract: An aptamer-based method for the ultrasensitive fluorescence detection of C-reactive protein (CRP) was developed using the ribonuclease H (RNase H) assisted DNA recycling signal amplification strategy. read more here.
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Published in 2020 at "Chemical communications"
DOI: 10.1039/d0cc02072a
Abstract: An intracellular signal amplification strategy was developed for the quantification of ATP in single cells by microchip electrophoresis with laser-induced fluorescence detection. By using the method proposed, intracellular ATP levels in single HeLa, HepG2 and… read more here.
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Published in 2022 at "Proceedings of the National Academy of Sciences of the United States of America"
DOI: 10.1073/pnas.2212378119
Abstract: Significance Thermoregulation in the mammalian body is mediated by a central brain thermostat. Because deep-brain temperatures are maintained within a narrow range, the thermostat must contain a sensor that can differentiate temperature fluctuations as small… read more here.