Efficient apoptosis requires feedback amplification of upstream apoptotic signals by effector caspase-3 or -7
Sign Up to like & getrecommendations! Published in 2019 at "Science Advances"
DOI: 10.1126/sciadv.aau9433
Abstract: Caspase-3 and -7 are redundantly required to amplify the extrinsic and intrinsic apoptotic cascade in human leukemia. Apoptosis is a complex multi-step process driven by caspase-dependent proteolytic cleavage cascades. Dysregulation of apoptosis promotes tumorigenesis and… read more here.
Keywords: caspase; apoptosis; upstream apoptotic; feedback amplification ... See more keywords