Modeling amplified p53 responses under DNA-PK inhibition in DNA damage response
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DOI: 10.18632/oncotarget.15062
Abstract: During DNA double strand breaks (DSBs) repair, coordinated activation of phosphatidylinositol 3-kinase (PI3K)-like kinases can activate p53 signaling pathway. Recent findings have identified novel interplays among these kinases demonstrating amplified first p53 pulses under DNA-PK… read more here.
Keywords: amplified p53; inhibition; dna inhibition; p53 responses ... See more keywords