Biological and synthetic surfactant exposure increases antimicrobial gene occurrence in a freshwater mixed microbial biofilm environment
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DOI: 10.1002/mbo3.1351
Abstract: Aquatic habitats are particularly susceptible to chemical pollution from domestic, agricultural, and industrial sources. Antimicrobials are commonly used in medical and industrial environments to reduce harmful bacteria and biofilms. This has led to the rapid… read more here.
Keywords: gene occurrence; biofilm; amr genes; gene ... See more keywords
Public health implications of plasmid-mediated quinolone and aminoglycoside resistance genes in Escherichia coli inhabiting a major anthropogenic river of India
Sign Up to like & getrecommendations! Published in 2022 at "Epidemiology and Infection"
DOI: 10.1017/s095026882200053x
Abstract: Abstract Presence of antimicrobial resistance (AMR) genes in Escherichia coli inhabiting anthropogenic rivers is an important public health concern because plasmid-mediated AMR genes can easily spread to other pathogens by horizontal gene transfer. Besides β-lactams,… read more here.
Keywords: genes escherichia; plasmid mediated; resistance; amr genes ... See more keywords
Combining short and long read sequencing to characterize antimicrobial resistance genes on plasmids applied to an unauthorized genetically modified Bacillus
Sign Up to like & getrecommendations! Published in 2020 at "Scientific Reports"
DOI: 10.1038/s41598-020-61158-0
Abstract: Antimicrobial resistance (AMR) is a major public health threat. Plasmids are able to transfer AMR genes among bacterial isolates. Whole genome sequencing (WGS) is a powerful tool to monitor AMR determinants. However, plasmids are difficult… read more here.
Keywords: long read; amr genes; modified bacillus; genetically modified ... See more keywords
A genomic epidemiological study shows that prevalence of antimicrobial resistance in Enterobacterales is associated with the livestock host, as well as antimicrobial usage.
Sign Up to like & getrecommendations! Published in 2021 at "Microbial genomics"
DOI: 10.1099/mgen.0.000630
Abstract: Enterobacterales from livestock are potentially important reservoirs for antimicrobial resistance (AMR) to pass through the food chain to humans, thereby increasing the AMR burden and affecting our ability to tackle infections. In this study 168… read more here.
Keywords: amr genes; antimicrobial resistance; resistance; antimicrobial usage ... See more keywords
Enterococcal Linear Plasmids Adapt to Enterococcus faecium and Spread within Multidrug-Resistant Clades
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DOI: 10.1128/aac.01619-22
Abstract: Antimicrobial resistance (AMR) of bacterial pathogens, including enterococci, is a global concern, and plasmids are crucial for spreading and maintaining AMR genes. Plasmids with linear topology were identified recently in clinical multidrug-resistant enterococci. ABSTRACT Antimicrobial… read more here.
Keywords: topology; linear plasmids; multidrug resistant; amr genes ... See more keywords
The DNA Phosphorothioation Restriction-Modification System Influences the Antimicrobial Resistance of Pathogenic Bacteria
Sign Up to like & getrecommendations! Published in 2023 at "Microbiology Spectrum"
DOI: 10.1128/spectrum.03509-22
Abstract: In this study, we demonstrated the effect of DNA PT modification-based R-M systems on horizontal gene transfer of AMR genes in pathogenic bacteria. We show that there is no apparent association between the genetic background… read more here.
Keywords: system; modification; pathogenic bacteria; amr genes ... See more keywords
Analysis of isolates from Bangladesh highlights multiple ways to carry resistance genes in Salmonella Typhi
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DOI: 10.1186/s12864-019-5916-6
Abstract: BackgroundTyphoid fever, caused by Salmonella Typhi, follows a fecal-oral transmission route and is a major global public health concern, especially in developing countries like Bangladesh. Increasing emergence of antimicrobial resistance (AMR) is a serious issue;… read more here.
Keywords: analysis isolates; amr genes; isolates bangladesh; resistance ... See more keywords
HAM-ART: An optimised culture-free Hi-C metagenomics pipeline for tracking antimicrobial resistance genes in complex microbial communities
Sign Up to like & getrecommendations! Published in 2022 at "PLoS Genetics"
DOI: 10.1371/journal.pgen.1009776
Abstract: Shotgun metagenomics is a powerful tool to identify antimicrobial resistance (AMR) genes in microbiomes but has the limitation that extrachromosomal DNA, such as plasmids, cannot be linked with the host bacterial chromosome. Here we present… read more here.
Keywords: ham art; resistance; pipeline; antimicrobial resistance ... See more keywords
A metagenomic glimpse into the gut of wild and domestic animals: Quantification of antimicrobial resistance and more
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DOI: 10.1371/journal.pone.0242987
Abstract: Antimicrobial resistance (AMR) in bacteria is a complex subject, why one need to look at this phenomenon from a wider and holistic perspective. The extensive use of the same antimicrobial classes in human and veterinary… read more here.
Keywords: metagenomic glimpse; amr genes; wild animals; antimicrobial resistance ... See more keywords
Microbial diversity and antimicrobial resistance in faecal samples from acute medical patients assessed through metagenomic sequencing
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DOI: 10.1371/journal.pone.0282584
Abstract: Antimicrobial resistance (AMR) is a threat to global public health. However, unsatisfactory approaches to directly measuring the AMR burden carried by individuals has hampered efforts to assess interventions aimed at reducing selection for AMR. Metagenomics… read more here.
Keywords: iqr iqr; diversity; faecal samples; amr genes ... See more keywords
Heightened variability observed in resistance and virulence genes across salmonella Kentucky isolates from poultry environments in British Columbia, Canada.
Sign Up to like & getrecommendations! Published in 2022 at "Food microbiology"
DOI: 10.2139/ssrn.4079321
Abstract: Many niche-dependent barriers along the poultry production continuum favour the survival of certain Salmonella serovars over others. Historically, the presence of particular serovars has been determined by niche-specific genes which encode resistance to selective pressures… read more here.
Keywords: british columbia; poultry; salmonella; virulence ... See more keywords