P294 AMT-101, a gut selective oral IL-10 fusion: results from a Phase 1b study in patients with active Ulcerative Colitis
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DOI: 10.1093/ecco-jcc/jjab076.418
Abstract: IL-10 is a pleiotropic anti-inflammatory cytokine that restores mucosal homeostasis. Genetic deficiencies in IL-10 cause intestinal inflammation in mice and are associated with early onset IBD in humans. In mice, this can be reversed by… read more here.
Keywords: gut selective; amt 101; fusion; patients active ... See more keywords