Single‐Nucleus RNA Sequencing Reveals that Decorin Expression in the Amygdala Regulates Perineuronal Nets Expression and Fear Conditioning Response after Traumatic Brain Injury
Sign Up to like & getrecommendations! Published in 2022 at "Advanced Science"
DOI: 10.1002/advs.202104112
Abstract: Traumatic brain injury (TBI) is a risk factor for posttraumatic stress disorder (PTSD). Augmented fear is a defining characteristic of PTSD, and the amygdala is considered the main brain region to process fear. The mechanism… read more here.
Keywords: traumatic brain; amygdala; tbi; expression ... See more keywords
Protracted dendritic growth in the typically developing human amygdala and increased spine density in young ASD brains
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24332
Abstract: The amygdala is a medial temporal lobe structure implicated in social and emotional regulation. In typical development (TD), the amygdala continues to increase volumetrically throughout childhood and into adulthood, while other brain structures are stable… read more here.
Keywords: age; spine density; asd; amygdala ... See more keywords
Neural oscillations in the infralimbic cortex after electrical stimulation of the amygdala. Relevance to acute stress processing
Sign Up to like & getrecommendations! Published in 2018 at "Journal of Comparative Neurology"
DOI: 10.1002/cne.24416
Abstract: The stress system coordinates the adaptive reactions of the organism to stressors. Therefore, dysfunctions in this circuit may correlate to anxiety‐related disorders, including depression. Comprehending the dynamics of this network may lead to a better… read more here.
Keywords: acute stress; stress; theta gamma; oscillations infralimbic ... See more keywords
Age‐specific and context‐specific responses of the medial extended amygdala in the developing prairie vole
Sign Up to like & getrecommendations! Published in 2018 at "Developmental Neurobiology"
DOI: 10.1002/dneu.22648
Abstract: The social needs of organisms change as they mature. Yet, little is known about the mechanisms that subserve processing social interactions or how these systems develop. The medial extended amygdala (meEA) is comprised of the… read more here.
Keywords: developing prairie; extended amygdala; amygdala; medial extended ... See more keywords
Questioning the role of amygdala and insula in an attentional capture by emotional stimuli task
Sign Up to like & getrecommendations! Published in 2020 at "Human Brain Mapping"
DOI: 10.1002/hbm.25290
Abstract: Our senses are constantly monitoring the environment for emotionally salient stimuli that are potentially relevant for survival. Because of our limited cognitive resources, emotionally salient distractors prolong reaction times (RTs) as compared to neutral distractors.… read more here.
Keywords: emotional stimuli; attentional capture; amygdala; capture emotional ... See more keywords
Neuromedin B excites central lateral amygdala neurons and reduces cardiovascular output and fear-potentiated startle.
Sign Up to like & getrecommendations! Published in 2023 at "Journal of cellular physiology"
DOI: 10.1002/jcp.31020
Abstract: Neuromedin B (NMB) and gastrin-releasing peptide (GRP) are the two mammalian analogs in the bombesin peptide family that exert a variety of actions including emotional processing, appetitive behaviors, cognition, and tumor growth. The bombesin-like peptides… read more here.
Keywords: potentiated startle; amygdala; bb1 receptors; fear potentiated ... See more keywords
Effects of lesions in different nuclei of the amygdala on conditioned taste aversion
Sign Up to like & getrecommendations! Published in 2017 at "Experimental Brain Research"
DOI: 10.1007/s00221-017-5078-1
Abstract: Conditioned taste aversion (CTA) is an adaptive learning that depends on brain mechanisms not completely identified. The amygdala is one of the structures that make up these mechanisms, but the involvement of its nuclei in… read more here.
Keywords: nuclei amygdala; basolateral complex; taste aversion; amygdala ... See more keywords
Low left amygdala volume is associated with a longer duration of unipolar depression
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Neural Transmission"
DOI: 10.1007/s00702-017-1811-y
Abstract: The amygdala plays a crucial role in the pathogenesis of major depressive disorder (MDD). While robust findings support a negative impact of illness duration on hippocampal volume in MDD, morphometric studies of the amygdala have… read more here.
Keywords: volume; mdd; duration; gmv ... See more keywords
The center of the emotional universe: Alcohol, stress, and CRF1 amygdala circuitry.
Sign Up to like & getrecommendations! Published in 2018 at "Alcohol"
DOI: 10.1016/j.alcohol.2018.03.009
Abstract: The commonalities between different phases of stress and alcohol use as well as the high comorbidity between alcohol use disorders (AUDs) and anxiety disorders suggest common underlying cellular mechanisms governing the rewarding and aversive aspects… read more here.
Keywords: alcohol stress; crf1; stress; center ... See more keywords
NMDA receptors in the avian amygdala and the premotor arcopallium mediate distinct aspects of appetitive extinction learning
Sign Up to like & getrecommendations! Published in 2018 at "Behavioural Brain Research"
DOI: 10.1016/j.bbr.2018.01.026
Abstract: HIGHLIGHTSWe investigate extinction learning with pigeons under appetitive conditions.We block NMDARs in the amygdala or the (pre)motor arcopallium during extinction.Blocking NMDARs in the amygdala impairs extinction acquisition.Blocking arcopallial NMDARs impairs consolidation of extinction memory.We show… read more here.
Keywords: consolidation; extinction; extinction learning; arcopallium ... See more keywords
Stress-Induced Differential Regulation Leads to Decoupling of the Activity between mPFC and Amygdala
Sign Up to like & getrecommendations! Published in 2017 at "Biophysical Journal"
DOI: 10.1016/j.bpj.2016.11.748
Abstract: Exposure to severe stress leads to the development of psychiatric disorders. Clinical studies have shown that three brain areas involved in learning and memory—the hippocampus, amygdala and medial prefrontal cortex (mPFC)—undergo distinct changes with stress… read more here.
Keywords: mpfc; fear expression; stress; amygdala ... See more keywords