Cyanide and lactate levels in patients during chronic oral amygdalin intake followed by intravenous amygdalin administration.
Sign Up to like & getrecommendations! Published in 2019 at "Complementary therapies in medicine"
DOI: 10.1016/j.ctim.2019.03.002
Abstract: The natural compound amygdalin has gained high popularity among tumor patients as a complementary or alternative treatment option. However, due to metabolization of amygdalin to cyanide (HCN) following oral consumption, there could be a high… read more here.
Keywords: lactate; amygdalin; amygdalin administration; cyanide ... See more keywords
Molecular mechanism of amygdalin action in vitro: review of the latest research
Sign Up to like & getrecommendations! Published in 2018 at "Immunopharmacology and Immunotoxicology"
DOI: 10.1080/08923973.2018.1441301
Abstract: Abstract Amygdalin, named as ‘laetrile’ and ‘vitamin B-17’ was initially supposed to be a safe drug for cancer treatment and was recognized by followers of natural medicine since it has been considered to be hydrolyzed… read more here.
Keywords: research; amygdalin; expression; molecular mechanism ... See more keywords
Synthesis, Characterization, and Antiproliferative Effect of CuO-TiO2-Chitosan-Amygdalin Nanocomposites in Human Leukemic MOLT4 Cells
Sign Up to like & getrecommendations! Published in 2022 at "Bioinorganic Chemistry and Applications"
DOI: 10.1155/2022/1473922
Abstract: The main aim of this study was to synthesize copper oxide- (CuO-) titanium oxide- (TiO2-) chitosan-amygdalin nanocomposites (CTCANc) and to characterize them physically and biologically (antimicrobial and anticancer activity using MOLT4 blood cancer cell line)… read more here.
Keywords: amygdalin nanocomposites; amygdalin; tio2 chitosan; cuo tio2 ... See more keywords
Amygdalin from Apricot Kernels Induces Apoptosis and Causes Cell Cycle Arrest in Cancer Cells: An Updated Review.
Sign Up to like & getrecommendations! Published in 2018 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520618666180105161136
Abstract: BACKGROUND Amygdalin is a cyanogenic glycoside which is described as a naturally occurring anticancer agent. Current review highlights apoptosis-inducing attributes of amygdalin towards different cancers and its potential application as an anti-cancer agent in cancer… read more here.
Keywords: amygdalin; cell cycle; review; cancer cells ... See more keywords
Anticancer effect of Amygdalin (vitamin B17) on hepatocellular carcinoma cell line(HepG2) in the presence and absence of Zinc.
Sign Up to like & getrecommendations! Published in 2020 at "Anti-cancer agents in medicinal chemistry"
DOI: 10.2174/1871520620666200120095525
Abstract: BACKGROUND Amygdalin (Vitamin B-17) is a naturally occurring vitamin found in the seeds of the fruits of Prunus Rosacea family including apricot, bitter almond, cherry, and peach. OBJECTIVE The purpose of this study was to… read more here.
Keywords: zinc; amygdalin; hepg2; cell ... See more keywords
Amygdalin as a chemoprotective agent in co-treatment with cisplatin
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Pharmacology"
DOI: 10.3389/fphar.2022.1013692
Abstract: Amygdalin is a naturally occurring glycoside used in traditional Chinese medicine and is known to have anti-cancer properties. Even though the anti-cancer properties of amygdalin are well known, its effect on normal cells has not… read more here.
Keywords: amygdalin; combination; treatment cisplatin; cisplatin ... See more keywords
Variation in Amygdalin Content in Kernels of Six Almond Species (Prunus spp. L.) Distributed in China
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2021.753151
Abstract: Amygdalin, a naturally occurring compound, is one of the main active ingredients of the Chinese raw bitter almond. The variation in amygdalin composition of seed kernels among the six almond species was determined, and relationships… read more here.
Keywords: six almond; variation amygdalin; amygdalin; almond ... See more keywords
Amygdalin: A Review on Its Characteristics, Antioxidant Potential, Gastrointestinal Microbiota Intervention, Anticancer Therapeutic and Mechanisms, Toxicity, and Encapsulation
Sign Up to like & getrecommendations! Published in 2022 at "Biomolecules"
DOI: 10.3390/biom12101514
Abstract: Bioactive amygdalin, found in high concentrations in bitter almonds, has been recognized as a symbol of the cyanogenic glycoside chemical organic substance, which was initially developed as a pharmaceutical for treating cancer after being hydrolyzed… read more here.
Keywords: antioxidant potential; amygdalin; potential gastrointestinal; toxicity ... See more keywords
In Vitro and In Vivo Evaluation of the Effectiveness and Safety of Amygdalin as a Cancer Therapy
Sign Up to like & getrecommendations! Published in 2022 at "Pharmaceuticals"
DOI: 10.3390/ph15111306
Abstract: Cancer is one of the most important causes of death worldwide. Several studies have shown the efficacy of apricot kernel seed as a cancer therapy due to the presence of amygdalin. These studies have demonstrated… read more here.
Keywords: formulation; amygdalin; aln gel; cancer therapy ... See more keywords
Host-microbiome metabolism of a plant toxin in bees
Sign Up to like & getrecommendations! Published in 2022 at "eLife"
DOI: 10.7554/elife.82595
Abstract: While foraging for nectar and pollen, bees are exposed to a myriad of xenobiotics, including plant metabolites, which may exert a wide range of effects on their health. Although the bee genome encodes enzymes that… read more here.
Keywords: metabolism; microbiota; amygdalin; amygdalin degradation ... See more keywords