Dietary wheat amylase trypsin inhibitors promote features of murine non-alcoholic fatty liver disease
Sign Up to like & getrecommendations! Published in 2019 at "Scientific Reports"
DOI: 10.1038/s41598-019-53323-x
Abstract: We previously demonstrated that a common dietary protein component, wheat amylase trypsin inhibitors (ATI), stimulate intestinal macrophages and dendritic cells via toll like receptor 4. Activation of these intestinal myeloid cells elicits an inflammatory signal… read more here.
Keywords: non alcoholic; wheat; trypsin inhibitors; amylase trypsin ... See more keywords
Comparative quantitative LC–MS/MS analysis of 13 amylase/trypsin inhibitors in ancient and modern Triticum species
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DOI: 10.1038/s41598-020-71413-z
Abstract: Amylase/trypsin inhibitors (ATIs) are major wheat allergens and they are also implicated in causing non-celiac gluten sensitivity and worsening other inflammatory conditions. With only few studies on ATI contents in different Triticum species available so… read more here.
Keywords: triticum species; wheat; trypsin inhibitors; amylase trypsin ... See more keywords
Lactobacilli Degrade Wheat Amylase Trypsin Inhibitors to Reduce Intestinal Dysfunction Induced by Immunogenic Wheat Proteins.
Sign Up to like & getrecommendations! Published in 2019 at "Gastroenterology"
DOI: 10.1053/j.gastro.2019.02.028
Abstract: BACKGROUND & AIMS Wheat-related disorders, a spectrum of conditions induced by the ingestion of gluten-containing cereals, have been increasing in prevalence. Patients with celiac disease have gluten-specific immune responses, but the contribution of non-gluten proteins… read more here.
Keywords: wheat; trypsin inhibitors; dysfunction; amylase trypsin ... See more keywords
LC-MS/MS quantitation of α-amylase/trypsin inhibitor CM3 and glutathione during wheat sourdough breadmaking.
Sign Up to like & getrecommendations! Published in 2021 at "Journal of applied microbiology"
DOI: 10.1111/jam.15346
Abstract: AIMS This study aimed to quantify α-amylase trypsin inhibitor (ATI) CM3 and glutathione (GSH) during wheat sourdough breadmaking. METHODS AND RESULTS Breads were made with two wheat cultivars and fermented with Fructilactobacillus sanfranciscensis, F. sanfranciscensis… read more here.
Keywords: wheat; cm3 glutathione; trypsin inhibitor; amylase trypsin ... See more keywords
Digestibility of wheat alpha-amylase/trypsin inhibitors using a caricain digestive supplement
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Nutrition"
DOI: 10.3389/fnut.2022.977206
Abstract: Wheat is a major source of nutrition, though in susceptible people it can elicit inappropriate immune responses. Wheat allergy and non-celiac wheat sensitivity are caused by various wheat proteins, including alpha-amylase trypsin inhibitors (ATIs). These… read more here.
Keywords: digestive supplement; alpha amylase; wheat; amylase trypsin ... See more keywords
Absolute and relative quantitation of amylase/trypsin-inhibitors by LC-MS/MS from wheat lines obtained by CRISPR-Cas9 and RNAi
Sign Up to like & getrecommendations! Published in 2022 at "Frontiers in Plant Science"
DOI: 10.3389/fpls.2022.974881
Abstract: Quantitation of wheat proteins is still a challenge, especially regarding amylase/trypsin-inhibitors (ATIs). A selection of ATIs was silenced in the common wheat cultivar Bobwhite and durum wheat cultivar Svevo by RNAi and gene editing, respectively,… read more here.
Keywords: wheat; amylase trypsin; trypsin inhibitors; relative quantitation ... See more keywords
Wheat Amylase Trypsin Inhibitors Aggravate Intestinal Inflammation Associated with Celiac Disease Mediated by Gliadin in BALB/c Mice
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DOI: 10.3390/foods11111559
Abstract: Celiac disease (CD) is an autoimmune intestinal disorder caused by the ingestion of gluten in people who carry the susceptible gene. In current celiac disease research, wheat gluten is often the main target of attention,… read more here.
Keywords: celiac disease; disease; wheat amylase; amylase trypsin ... See more keywords
Sourdough Fermentation Degrades Wheat Alpha-Amylase/Trypsin Inhibitor (ATI) and Reduces Pro-Inflammatory Activity
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DOI: 10.3390/foods9070943
Abstract: The ingestion of gluten-containing foods can cause wheat-related disorders in up to 15% of wheat consuming populations. Besides the role of gluten, α-amylase/trypsin inhibitors (ATI) have recently been identified as inducers of an innate immune… read more here.
Keywords: fermentation; inflammatory activity; amylase trypsin; ati tetramers ... See more keywords
Amylase Trypsin Inhibitors (ATIs) in a Selection of Ancient and Modern Wheat: Effect of Genotype and Growing Environment on Inhibitory Activities
Sign Up to like & getrecommendations! Published in 2022 at "Plants"
DOI: 10.3390/plants11233268
Abstract: Wheat amylase-trypsin inhibitors (ATIs) are a family of plant defense proteins with an important role in human health for their involvement in allergies, celiac disease and non-celiac wheat sensitivity. Information about the differences in ATI… read more here.
Keywords: wheat; amylase trypsin; inhibitory; growing environment ... See more keywords