Palatable food access impacts expression of amylin receptor components in the mesocorticolimbic system
Sign Up to like & getrecommendations! Published in 2020 at "Experimental Physiology"
DOI: 10.1113/ep088356
Abstract: What is the central question of this study? We tested whether intra‐nucleus accumbens core amylin receptor (AmyR) activation suppresses feeding and evaluated whether intake of palatable food influences mesocorticolimbic AmyR expression. What is the main… read more here.
Keywords: palatable food; food access; amylin receptor; food ... See more keywords
Role of microglial amylin receptors in mediating beta amyloid (Aβ)-induced inflammation
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DOI: 10.1186/s12974-017-0972-9
Abstract: BackgroundNeuroinflammation in the brain consequent to activation of microglia is viewed as an important component of Alzheimer’s disease (AD) pathology. Amyloid beta (Aβ) protein is known to activate microglia and unleash an inflammatory cascade that… read more here.
Keywords: amyloid; amylin receptor; amylin receptors; beta ... See more keywords
Extracellular vesicles enriched with amylin receptor are cytoprotective against the Aß toxicity in vitro
Sign Up to like & getrecommendations! Published in 2022 at "PLoS ONE"
DOI: 10.1371/journal.pone.0267164
Abstract: Extracellular vesicles (EVs) are double membrane structures released by all cell types with identified roles in the generation, transportation, and degradation of amyloid-β protein (Aβ) oligomers in Alzheimer’s disease (AD). EVs are thus increasingly recognized… read more here.
Keywords: enriched amylin; vesicles enriched; receptor cytoprotective; cytoprotective toxicity ... See more keywords