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   Articles with "amyloid angiopathy" as a keyword



Chronic Stress Exacerbates Cerebral Amyloid Angiopathy Through Promoting Neutrophil Extracellular Traps Formation

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recommendations! Published in 2024 at "Advanced Science"

DOI: 10.1002/advs.202404096

Abstract: Cerebral amyloid angiopathy (CAA) is the leading cause of vascular dementia among the elderly. Neuropsychiatric symptoms are commonly manifested in cerebral amyloid angiopathy patients but are usually considered as consequences of cerebral amyloid angiopathy pathology.… read more here.

Keywords: cerebral amyloid; amyloid angiopathy; formation; chronic stress ... See more keywords

Progressive White Matter Injury in Preclinical Dutch Cerebral Amyloid Angiopathy

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recommendations! Published in 2022 at "Annals of Neurology"

DOI: 10.1002/ana.26429

Abstract: Autosomal‐dominant, Dutch‐type cerebral amyloid angiopathy (D‐CAA) offers a unique opportunity to develop biomarkers for pre‐symptomatic cerebral amyloid angiopathy (CAA). We hypothesized that neuroimaging measures of white matter injury would be present and progressive in D‐CAA… read more here.

Keywords: matter; amyloid angiopathy; white matter; cerebral amyloid ... See more keywords

Decreased Cerebrospinal Fluid Amyloid β 38, 40, 42, and 43 Levels in Sporadic and Hereditary Cerebral Amyloid Angiopathy

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recommendations! Published in 2023 at "Annals of Neurology"

DOI: 10.1002/ana.26610

Abstract: Vascular amyloid β (Aβ) accumulation is the hallmark of cerebral amyloid angiopathy (CAA). The composition of cerebrospinal fluid (CSF) of CAA patients may serve as a diagnostic biomarker of CAA. We studied the diagnostic potential… read more here.

Keywords: amyloid angiopathy; caa; cerebrospinal fluid; amyloid ... See more keywords

Study on the Therapeutic Effects of Bisdemethoxycurcumin on a Cerebral Amyloid Angiopathy Mouse Model Established via Chronic Treatment With Five Vascular Risk Factors

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recommendations! Published in 2025 at "Brain and Behavior"

DOI: 10.1002/brb3.70245

Abstract: Cerebral amyloid angiopathy (CAA) is recognized as a major contributor to progressive cognitive decline and cerebral hemorrhages in the elderly population. Currently, there is a global shortage of safe and effective treatments for this condition.… read more here.

Keywords: cerebral amyloid; effects bisdemethoxycurcumin; amyloid angiopathy; study therapeutic ... See more keywords

Differences in the cerebral amyloid angiopathy proteome in Alzheimer’s disease and mild cognitive impairment

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recommendations! Published in 2024 at "Acta Neuropathologica"

DOI: 10.1007/s00401-024-02767-1

Abstract: Cerebral amyloid angiopathy (CAA) is characterized by amyloid beta (Aβ) deposition in cerebrovasculature. It is prevalent with aging and Alzheimer’s disease (AD), associated with intracerebral hemorrhage, and contributes to cognitive deficits. To better understand molecular… read more here.

Keywords: cerebral amyloid; caa vessels; amyloid angiopathy; proteome ... See more keywords

Lipid mediated formation of antiparallel aggregates in cerebral amyloid angiopathy

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recommendations! Published in 2025 at "Acta Neuropathologica"

DOI: 10.1007/s00401-025-02911-5

Abstract: Cerebral amyloid angiopathy (CAA) is a cerebrovascular disorder marked by amyloid-β (Aβ) deposition in blood vessel walls, leading to hemorrhage and recurring stroke. Despite significant overlap with Alzheimer’s disease (AD) through shared Aβ pathology, the… read more here.

Keywords: cerebral amyloid; lipid mediated; formation antiparallel; amyloid angiopathy ... See more keywords
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Cerebral amyloid angiopathy: subtypes, treatment and role in cognitive impairment

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recommendations! Published in 2017 at "Journal of Neurology"

DOI: 10.1007/s00415-017-8608-7

Abstract: Accumulation of β amyloid in leptomeningeal vessels and cortical arterioles is the hallmark of cerebral amyloid angiopathy, this causes vessel stiffening, and vessel wall rupture. Alzheimer’s disease amyloid plaques are composed of β-amyloid 42, whilst… read more here.

Keywords: amyloid angiopathy; cerebral amyloid; amyloid; clearance ... See more keywords
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Patterns of convexal subarachnoid haemorrhage: clinical, radiological and outcome differences between cerebral amyloid angiopathy and other causes

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recommendations! Published in 2017 at "Journal of Neurology"

DOI: 10.1007/s00415-017-8693-7

Abstract: BackgroundCerebral amyloid angiopathy (CAA) is a common aetiology of convexal subarachnoid haemorrhage (cSAH) but little is known about its specific characteristics in comparison with cSAH from other causes. In this study we compared patients with… read more here.

Keywords: amyloid angiopathy; convexal subarachnoid; caa; subarachnoid haemorrhage ... See more keywords

Recurrent intracerebral hemorrhage in patients with cerebral amyloid angiopathy: a propensity-matched case–control study

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recommendations! Published in 2022 at "Journal of Neurology"

DOI: 10.1007/s00415-021-10937-4

Abstract: Objective Cerebral amyloid angiopathy (CAA) can present with intracerebral hemorrhage (ICH), convexity subarachnoid hemorrhage (SAH), and rarely acute ischemic stroke (AIS). The objective of our study was to compare the readmission rates for recurrent ICH,… read more here.

Keywords: caa; study; amyloid angiopathy; cerebral amyloid ... See more keywords

Predictors of localization, outcome, and etiology of spontaneous intracerebral hemorrhages: focus on cerebral amyloid angiopathy

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recommendations! Published in 2020 at "Journal of Neural Transmission"

DOI: 10.1007/s00702-020-02174-2

Abstract: Despite its clinical relevance, cerebral amyloid angiopathy (CAA) is underdiagnosed worldwide. This retrospective study aimed to assess the incidence, etiology, predictors, and outcome of intracerebral hemorrhages (ICHs) in this region, with special focus on possible… read more here.

Keywords: amyloid angiopathy; cerebral amyloid; etiology; lobar cerebellar ... See more keywords

Perfusion-weighted MRI in cerebral amyloid angiopathy-related transient focal neurological episodes

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recommendations! Published in 2021 at "Neurological Sciences"

DOI: 10.1007/s10072-021-05195-1

Abstract: Sporadic cerebral amyloid angiopathy (CAA) is a common age-related cerebral small vessel disease characterized by progressive ß-amyloid deposition in the walls of small cortical arteries, arterioles, and capillaries in the cerebral cortex and overlying leptomeninges.… read more here.

Keywords: amyloid angiopathy; cerebral amyloid; related transient; perfusion ... See more keywords