Herpes simplex virus encoded ICP6 protein forms functional amyloid assemblies with necroptosis-associated host proteins.
Sign Up to like & getrecommendations! Published in 2020 at "Biophysical chemistry"
DOI: 10.1016/j.bpc.2020.106524
Abstract: The viral protein ICP6, encoded by herpes simplex virus 1 (HSV-1), harbours a RIP-homotypic interaction motif (RHIM), that plays a role in viral inhibition of host cell death pathways. Other members of the Herpesviridae family… read more here.
Keywords: protein; amyloid assemblies; rhim; host ... See more keywords
Engineering and evaluation of amyloid assemblies as a nanovaccine against the Chikungunya virus.
Sign Up to like & getrecommendations! Published in 2018 at "Nanoscale"
DOI: 10.1039/c8nr05948a
Abstract: The design of nanoparticles exposing a high density of antigens constitutes a promising strategy to address safety concerns of conventional life-attenuated vaccines as well as to increase the immunogenicity of subunit vaccines. In this study,… read more here.
Keywords: chikungunya virus; engineering evaluation; amyloid assemblies; microscopy ... See more keywords