Discerning Modulation of α-Synuclein Amyloid Assembly by α-Crystallin.
Sign Up to like & getrecommendations! Published in 2023 at "ACS chemical neuroscience"
DOI: 10.1021/acschemneuro.3c00052
Abstract: Altered protein folding leading to the formation of structured aggregates such as amyloid fibrils has gained significant attention due to its association with neurodegenerative diseases. α-Synuclein, a small intrinsically disordered protein, gets transformed into amyloid… read more here.
Keywords: crystallin; modulation synuclein; chaperone like; synuclein amyloid ... See more keywords
Tachykinin Neuropeptides and Amyloid β (25-35) Assembly: Friend or Foe?
Sign Up to like & getrecommendations! Published in 2022 at "Journal of the American Chemical Society"
DOI: 10.1021/jacs.2c03845
Abstract: Amyloid β (Aβ) protein is responsible for Alzheimer's disease, and one of its important fragments, Aβ(25-35), is found in the brain and has been shown to be neurotoxic. Tachykinin neuropeptides, including Neuromedin K (NK), Kassinin,… read more here.
Keywords: substance; tachykinin; tachykinin neuropeptides; neuropeptides amyloid ... See more keywords