Low-molecular-weight chondroitin sulfate attenuated injury by inhibiting oxidative stress in amyloid &bgr;-treated SH-SY5Y cells
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DOI: 10.1097/wnr.0000000000001092
Abstract: The neurotoxicity of aggregated amyloid &bgr; (A&bgr;) has been implicated as a critical cause in the pathogenesis of Alzheimer’s disease. In a previous work, we have shown that low-molecular-weight chondroitin sulfate (LMWCS), a derivative of… read more here.
Keywords: amyloid bgr; bgr; sy5y cells; chondroitin sulfate ... See more keywords
Plumbagin inhibits amyloid-&bgr;-induced neurotoxicity: regulation of oxidative stress and nuclear factor erythroid 2-related factor 2 activation
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DOI: 10.1097/wnr.0000000000001103
Abstract: &bgr;-Amyloid (A&bgr;) species probably exert neurotoxic effects in Alzheimer’s disease. In the present study, the effect of antioxidant plumbagin was tested against A&bgr;25–35-induced neurotoxicity in the SH-SY5Y cell line. Cell viability was determined using an… read more here.
Keywords: bgr; plumbagin; bgr induced; nuclear factor ... See more keywords
Effects of Androgens on the Amyloid-&bgr; Protein in Alzheimer's Disease
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DOI: 10.1210/en.2018-00660
Abstract: Age-related androgen depletion has been implicated in compromised neuroprotection and is involved in the pathogenesis of neurodegenerative disease, including Alzheimer's disease (AD), the leading cause of dementia. Emerging data revealed that reduction of both serum… read more here.
Keywords: androgens amyloid; effects androgens; alzheimer disease; disease ... See more keywords