Association of β-Amyloid Burden With Sleep Dysfunction and Cognitive Impairment in Elderly Individuals With Cognitive Disorders
Sign Up to like & getrecommendations! Published in 2019 at "JAMA Network Open"
DOI: 10.1001/jamanetworkopen.2019.13383
Abstract: Key Points Question Is β-amyloid deposition in the brain associated with sleep dysfunction and cognition in elderly individuals with cognitive disorders? Findings In this survey study of 52 participants aged 65 years and older, β-amyloid… read more here.
Keywords: elderly individuals; cognitive impairment; cognitive disorders; individuals cognitive ... See more keywords
Rapid Eye Movement Sleep, Neurodegeneration, and Amyloid Deposition in Aging
Sign Up to like & getrecommendations! Published in 2023 at "Annals of Neurology"
DOI: 10.1002/ana.26604
Abstract: Rapid eye movement (REM) sleep is markedly altered in Alzheimer's disease (AD), and its reduction in older populations is associated with AD risk. However, little is known about the underlying brain mechanisms. Our objective was… read more here.
Keywords: eye movement; rapid eye; amyloid deposition;
Mitral and tricuspid stenosis caused by light chain cardiac amyloid deposition
Sign Up to like & getrecommendations! Published in 2020 at "ESC Heart Failure"
DOI: 10.1002/ehf2.12668
Abstract: Cardiac amyloidosis results in an infiltrative restrictive cardiomyopathy, with a number of characteristic features: biventricular hypertrophy, abnormal myocardial global longitudinal strain with relative apical sparing, biatrial dilation, and small pericardial effusion along with conduction abnormalities.… read more here.
Keywords: mitral tricuspid; light chain; stenosis; amyloid deposition ... See more keywords
Indirect evaluation of amyloid deposition by ultrasonography and its relationship with MEFV gene mutation in FMF patients
Sign Up to like & getrecommendations! Published in 2022 at "Journal of Clinical Ultrasound"
DOI: 10.1002/jcu.23409
Abstract: The most significant complication in familial mediterranean fever (FMF) patients is dysfunction and organ failure developing depending on amyloid deposition in organs. The golden standard for showing amyloid deposition is the biopsy; however, tissue stiffness… read more here.
Keywords: fmf patients; gene mutation; deposition; relationship mefv ... See more keywords
Clinical and imaging correlates of amyloid deposition in dementia with Lewy bodies
Sign Up to like & getrecommendations! Published in 2018 at "Movement Disorders"
DOI: 10.1002/mds.27403
Abstract: Background: Amyloid deposition is common in dementia with Lewy bodies, but its pathophysiological significance is unclear. read more here.
Keywords: lewy bodies; clinical imaging; dementia lewy; amyloid deposition ... See more keywords
Characterization of an 'Amyloid Only' Transgenic (B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax) Mouse Model of Alzheimer's Disease.
Sign Up to like & getrecommendations! Published in 2017 at "Journal of comparative pathology"
DOI: 10.1016/j.jcpa.2017.03.001
Abstract: The spatiotemporal pattern of cerebral amyloid deposition, detectable as light microscopically recognizable aggregates in an 'amyloid only' transgenic mouse model of Alzheimer's disease, B6C3-Tg(APPswe,PSEN1dE9)85Dbo/Mmjax, is reported for the first time in this strain. Monoclonal and polyclonal… read more here.
Keywords: alzheimer disease; appswe psen1de9; b6c3 appswe; disease ... See more keywords
New clinical forms of hereditary apoA-I amyloidosis entail both glomerular and retinal amyloidosis.
Sign Up to like & getrecommendations! Published in 2020 at "Kidney international"
DOI: 10.1016/j.kint.2020.03.033
Abstract: Apolipoprotein A1 amyloidosis (ApoAI) results from specific mutations in the APOA1 gene causing abnormal accumulation of amyloid fibrils in diverse tissues. The kidney is a prominent target tissue in ApoAI amyloidosis with a remarkable selectivity… read more here.
Keywords: new clinical; apoa amyloid; apoai amyloidosis; amyloidosis ... See more keywords
Impact of APOE-ε4 carriage on the onset and rates of neocortical Aβ-amyloid deposition
Sign Up to like & getrecommendations! Published in 2020 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2020.06.001
Abstract: Neocortical Aβ-amyloid deposition, one of the hallmark pathologic features of Alzheimer's disease (AD), begins decades prior to the presence of clinical symptoms. As clinical trials move to secondary and even primary prevention, understanding the rates… read more here.
Keywords: neocortical amyloid; apoe carriage; age; amyloid deposition ... See more keywords
Molecular imaging of beta-amyloid deposition in late-life depression
Sign Up to like & getrecommendations! Published in 2021 at "Neurobiology of Aging"
DOI: 10.1016/j.neurobiolaging.2021.01.002
Abstract: Late-life depression (LLD) is associated with an increased risk of all-cause dementia and may involve Alzheimer's disease pathology. Twenty-one LLD patients who met the Diagnostic and Statistical Manual of Mental Disorders, Fifth Edition, criteria for… read more here.
Keywords: depression; lld patients; life depression; beta amyloid ... See more keywords
Prognostic plasma protein panel for Aβ deposition in the brain in Alzheimer’s disease
Sign Up to like & getrecommendations! Published in 2019 at "Progress in Neurobiology"
DOI: 10.1016/j.pneurobio.2019.101690
Abstract: Alzheimer's disease (AD) is the most common age-associated dementia. Many studies have sought to predict cerebral amyloid deposition, the major pathological hallmark of AD, using body fluids such as blood or cerebral spinal fluid (CSF).… read more here.
Keywords: alzheimer disease; deposition; blood; amyloid deposition ... See more keywords
Genome-wide association study of brain amyloid deposition as measured by Pittsburgh Compound-B (PiB)-PET imaging
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Psychiatry"
DOI: 10.1038/s41380-018-0246-7
Abstract: Deposition of amyloid plaques in the brain is one of the two main pathological hallmarks of Alzheimer’s disease (AD). Amyloid positron emission tomography (PET) is a neuroimaging tool that selectively detects in vivo amyloid deposition… read more here.
Keywords: genome wide; deposition; pib pet; amyloid deposition ... See more keywords