In Situ Tissue Labeling of Cerebral Amyloid Using HIV-Related Tat Peptide
Sign Up to like & getrecommendations! Published in 2018 at "Molecular Neurobiology"
DOI: 10.1007/s12035-018-0870-x
Abstract: Delivering peptide-based drugs to the brain is a major challenge because of the existence of the blood-brain barrier (BBB). To overcome this problem, cell-penetrating peptides derived from proteins that are able to cross biological membranes… read more here.
Keywords: peptide; amyloid deposits; tissue; tat peptide ... See more keywords
Complement in autoimmune inflammatory myopathies, the role of myositis-associated antibodies, COVID-19 associations, and muscle amyloid deposits
Sign Up to like & getrecommendations! Published in 2022 at "Expert Review of Clinical Immunology"
DOI: 10.1080/1744666x.2022.2054803
Abstract: ABSTRACT Introduction The inflammatory myopathies (IM) have now evolved into distinct subsets requiring clarification about their immunopathogenesis to guide applications of targeted therapies Areas covered Immunohistopathologic criteria of IM with a focus on complement, anti-complement… read more here.
Keywords: amyloid deposits; myositis; complement; muscle amyloid ... See more keywords
Skin amyloid deposits and nerve fiber loss as markers of neuropathy onset and progression in hereditary transthyretin amyloidosis
Sign Up to like & getrecommendations! Published in 2022 at "European Journal of Neurology"
DOI: 10.1111/ene.15268
Abstract: This study was undertaken to assess skin biopsy as a marker of disease onset and severity in hereditary transthyretin amyloidosis with polyneuropathy (ATTRv‐PN), a treatable disease. read more here.
Keywords: skin amyloid; amyloid deposits; transthyretin amyloidosis; hereditary transthyretin ... See more keywords
Transthyretin amyloid deposits in lumbar spinal stenosis and assessment of signs of systemic amyloidosis
Sign Up to like & getrecommendations! Published in 2020 at "Journal of Internal Medicine"
DOI: 10.1111/joim.13222
Abstract: Wild‐type transthyretin (ATTRwt) amyloidosis is the most common systemic amyloidosis in Western countries and manifests mainly as progressive restrictive cardiomyopathy. read more here.
Keywords: amyloid deposits; amyloidosis; systemic amyloidosis; deposits lumbar ... See more keywords
Nanoparticles targeting amyloid deposits: a potential contrast agent for diagnosis and treatment
Sign Up to like & getrecommendations! Published in 2021 at "Journal of Nanophotonics"
DOI: 10.1117/1.jnp.15.026010
Abstract: Abstract. Amyloid-based diseases, such as amyloid light-chain amyloidosis, are characterized by misfolding of proteins and their deposition as amyloids in tissues. As prognosis is usually poor, patients suffering from these illnesses can benefit from improved… read more here.
Keywords: targeting amyloid; nanoparticles targeting; treatment; amyloid ... See more keywords
FRI0026 SYSTEMIC, RENAL AND CARDIAC AA AMYLOIDOSIS IN RHEUMATOID ARTHRITIS – A COMPARATIVE POSTMORTEM CLINICOPATHOLOGIC STUDY OF 161 PATIENTS
Sign Up to like & getrecommendations! Published in 2019 at "Annals of the Rheumatic Diseases"
DOI: 10.1136/annrheumdis-2019-eular.603
Abstract: Objectives: The aim of our study was to determine the incidence of systemic AA amyloidosis (sAAa) in RA, to appraise the prevalence and severity of amyloid A deposits in different tissue structures of the kidneys… read more here.
Keywords: heart; renal cardiac; amyloid deposits; deposition ... See more keywords
The unresolved problem of beta-2 microglobulin amyloid deposits in the intervertebral discs of long-term dialysis patients
Sign Up to like & getrecommendations! Published in 2017 at "Journal of Orthopaedic Surgery and Research"
DOI: 10.1186/s13018-017-0697-6
Abstract: BackgroundDialysis-related destructive spondyloarthropathy caused by beta-2 microglobulin (β2M) amyloid deposits in intervertebral discs is a major burden for patients undergoing long-term dialysis. This study aimed to quantify the presence of β2M amyloid deposits in the… read more here.
Keywords: term dialysis; long term; amyloid deposits; dialysis patients ... See more keywords