Amyloid Aggregation of Bacillus circulans Xylanase under Native Conditions and its Modulation by β‐Amyloid‐Derived Peptide Fragments
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DOI: 10.1002/cbic.201800472
Abstract: The aggregation of intrinsically disordered proteins into fibrils is implicated in many neurodegenerative diseases. Amyloid aggregation is a generic property of proteins as evidenced by globular proteins that often form amyloid aggregates under partially denaturing… read more here.
Keywords: circulans xylanase; aggregation; amyloid derived; amyloid aggregation ... See more keywords
Amyloid β-Derived Diffusible Ligands (ADDLs) Induce Abnormal Autophagy Associated with Aβ Aggregation Degree
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DOI: 10.1007/s12031-017-1015-9
Abstract: Autophagy is disturbed in Alzheimer’s disease (AD) and maintaining normal autophagy homeostasis is a new therapeutic strategy for AD treatment. Amyloid β-derived diffusible ligands (ADDLs), the most toxic species of which are oligomeric forms of… read more here.
Keywords: aggregation; amyloid; derived diffusible; amyloid derived ... See more keywords