Intracellular amyloid-β disrupts tight junctions of the retinal pigment epithelium via NF-κB activation
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DOI: 10.1016/j.neurobiolaging.2020.07.013
Abstract: Drusen are focal deposits between the retinal pigment epithelium (RPE) and Bruch's membrane in the retina of patients with age-related macular degeneration. Amyloid-β is one of the important components of drusen, which leads to local… read more here.
Keywords: intracellular amyloid; amyloid; pigment epithelium; tight junctions ... See more keywords