The Upper Hand of the Otu Amyloid Fibers: Increasing Enzymatic Activity and Prolonging Lifespan.
Sign Up to like & getrecommendations! Published in 2019 at "Molecular cell"
DOI: 10.1016/j.molcel.2019.03.038
Abstract: The formation of amyloid fibers is usually associated with aging and neurodegeneration. In this issue of Molecular Cell, Ji et al. (2019) demonstrate that the deubiquitinase Otu coalesces into amyloid-like fibers to enhance its activity and… read more here.
Keywords: otu amyloid; otu; upper hand; amyloid fibers ... See more keywords
Hierarchically Fabricated Amyloid Fibers via Evaporation-Induced Self-Assembly.
Sign Up to like & getrecommendations! Published in 2021 at "ACS nano"
DOI: 10.1021/acsnano.1c08374
Abstract: Multiscale hierarchical nano- and microstructures of amyloid fibrils are fabricated by evaporation-induced self-assembly combined with topographic surface patterning techniques. The continuous stick-and-slip motion induces uniaxial alignment of amyloid fibrils characterized by high orientational order during… read more here.
Keywords: self assembly; induced self; microscopy; evaporation induced ... See more keywords
Nucleophilic Regulation of the Formation of Melanin-like Species by Amyloid Fibers.
Sign Up to like & getrecommendations! Published in 2022 at "ACS omega"
DOI: 10.1021/acsomega.1c05399.s001
Abstract: This work examines the influences of amyloid fibers of hen egg white lysozyme (HEWL) on the formation of melanin-like species (MLS) with a rationally selected set of catechol derivatives. Catechol-amyloid interactions, which are central in… read more here.
Keywords: formation melanin; melanin like; amyloid fibers; like species ... See more keywords
Mass and charge distributions of amyloid fibers involved in neurodegenerative diseases: mapping heterogeneity and polymorphism† †Electronic supplementary information (ESI) available: Experimental section and supplementary figures. See DOI: 10.1039/c7sc04542e
Sign Up to like & getrecommendations! Published in 2018 at "Chemical Science"
DOI: 10.1039/c7sc04542e
Abstract: Characterization by charge detection mass spectrometry of amyloid fibers involved in neurodegenerative diseases: Aβ peptide, tau and α-synuclein. read more here.
Keywords: involved neurodegenerative; amyloid fibers; charge; neurodegenerative diseases ... See more keywords
Label-free imaging of amyloids using their intrinsic linear and nonlinear optical properties.
Sign Up to like & getrecommendations! Published in 2017 at "Biomedical optics express"
DOI: 10.1364/boe.8.000743
Abstract: The optical properties of amyloid fibers are often distinct from those of the source protein in its non-fibrillar form. These differences can be utilized for label-free imaging or characterization of such structures, which is particularly… read more here.
Keywords: free imaging; fluorescence; amyloid fibers; optical properties ... See more keywords
Beyond Amyloid Fibers: Accumulation, Biological Relevance, and Regulation of Higher-Order Prion Architectures
Sign Up to like & getrecommendations! Published in 2022 at "Viruses"
DOI: 10.3390/v14081635
Abstract: The formation of amyloid fibers is associated with a diverse range of disease and phenotypic states. These amyloid fibers often assemble into multi-protofibril, high-order architectures in vivo and in vitro. Prion propagation in yeast, an… read more here.
Keywords: prion; fibers accumulation; beyond amyloid; amyloid fibers ... See more keywords